Complicated Onychomycosis in Patients with Metabolic Syndrome: Clinical Aspects of Deviation in the Laboratory Signs of Endothelial Dysfunction and Polyhypovitaminosis
Journal Title: Міжнародний ендокринологічний журнал - Year 2015, Vol 5, Issue 69
Abstract
The study involved 93 patients aged 52 to 85 years with metabolic syndrome and concomitant complicated fungal nail infection. In all patients we have measured the levels of nitric oxide and endothelin-1. The content of B1, B2, PP, B6 and C vitamins in the blood, and urine excretion of derivatives before and during the treatment of patients with destructive onychomycosis were studied. It is noted that in the majority of patients (aged over 50 years) with polyоnychomycosis and comorbid underlying metabolic syndrome has endothelial dysfunction and multivitamin deficiency that requires correction.
Authors and Affiliations
O. N. Nadashkevich, A. R. Verhun, Z. M. Kit, O. M. Verhun
Keywords
Related Articles
- EP ID EP219672
- DOI -
- Views 26
- Downloads 0
Thiamine derivatives and vitamin B1 analogues: biochemical, structural and pathway analysis and its implication in the pathobiology of diabetic complications
Thiamіne acts as a coenzyme for transketolase and for the pyruvate dehydrogenase and α-ketoglutarate dehydrogenase complexes, whіch enzymes play a fundamental role in intracellular glucose metabolіsm. The relatіonship b...
Assessment of somatotropic function in children with syndrome of biologically inactive growth hormone against a background of clonidine and insulin stimulation tests
Background. Growth pathology caused by somatotropic insufficiency is one of the most urgent problems in pediatric endocrinology. An increase in the growth hormone (GH) level less than 10 ng/ml was traditionally consider...
The Endothelium Dysfunction as a Possible Promoter of Development of Non-Functional Pituitary Adenoma
Recently the term of endothelial dysfunction has obtained a wide circulation in clinical neuroendocrinology. The phenomenon plays a significant role in genesis of many cerebrovascular brain pathological conditions. In mo...
The State of Microbiota of the Large Intestine in Patients with Type 1 Diabetes Mellitus Depending on the Age and Duration of the Disease
Introduction. Intestinal dysbiosis against the background of type 1 diabetes mellitus (DM) results in the development and unfavourable clinical course of chronic diseases, in particular of ENT-organs. Objective of the st...
Comments on the 2018 European Thyroid Association Guidelines for the management of amiodarone-associated thyroid dysfunction
In this article, the authors described and commented the main provisions of the new guidelines for the examination and treatment of patients with amiodarone-associated thyroid dysfunction. Their text is divided thematica...