Complications of Allogeneic Blood Transfusion: Current Approach to Diagnosis and Management

Journal Title: International Blood Research & Reviews - Year 2015, Vol 3, Issue 4

Abstract

Introduction: Blood transfusion remains a vital component of modern medicine, as yet artificial blood or blood substitute is still widely promising. In well-organized health care systems, with standard transfusion services/facilities and safe practices, the risk associated with infusion of allogeneic blood components is minimal or negligible. However, in most developing nations, significant morbidity is still associated with allogeneic blood transfusion. Objective: This article is a review on diagnosis of transfusion reactions and modalities for treatment, aimed at promoting interest and awareness as well as, providing current knowledge regarding blood transfusion complications among clinical staff involved in transfusion care. Methodology: Relevant literatures were searched using search engines such as PubMed and Google Scholar, as well as standard textbooks in transfusion medicine. Results were summarized in appropriate sections. Results: There are several complications associated with allogeneic blood transfusion. Many of these complications can be prevented and controlled through effective donor and recipient haemovigilance, as well as training and re-training of both clinical and blood bank staff. Conclusion: Improved knowledge regarding these complications, as well as current treatment guidelines is a crucial strategy to their prevention and control in developing nations. This will invariably increase the capacity and ability of the attending clinical staff (physicians/nurses) to correctly identify, manage and report these adverse transfusion reactions.

Authors and Affiliations

Ademola S. Adewoyin, Olayinka A. Oyewale

Keywords

Related Articles

Isolation and Antibiotic Susceptibility Pattern of Bacteria Associated with Blood Stream Infections

Aim: To determine the pattern of bacterial agents responsible for blood stream infection and determine the antibiotic susceptibility pattern of the bacterial isolates. Study Design: Experimental Place and Duration of Stu...

Prevalence of HBV and HCV Infections among Blood Donors in Northeast Libya

Background: Blood donation is a very important life-saving intervention in health care services. Post transfusion infections such as hepatitis and human immunodeficiency virus infection continues to be an important publi...

Hematological Changes Following Oral Administration of Aqueous Root Bark Extract of Salacia lehmbachii in Albino Rats

Objective: This study investigated the effects of oral administration of aqueous root bark extract of Salacia lehmbachii on some haematological indices in albino rats. Methodology: Twenty-four male rats weighing 180-200...

Case Report: Portal Vein Thrombosis as a Cause of Haematemesis in a Healthy African Adolescent

Introduction: Thromboembolic incidents typically occur as deep vein thrombosis of the limbs and pulmonary embolism but can also occur in unusual sites such as cerebral or sinus, mesenteric, portal, hepatic renal and reti...

Prevalence of Clinically Significant Alloantibodies among Transfusion Requiring Patients in a Tertiary Hospital in Sokoto, Nigeria

Aim: No data are available regarding the frequencies of clinically significant alloantibodies among patients requiring transfusion in Sokoto North western Nigeria. We intend to provide information on the prevalence of cl...

Download PDF file
  • EP ID EP242477
  • DOI 10.9734/IBRR/2015/17874
  • Views 117
  • Downloads 0

How To Cite

Ademola S. Adewoyin, Olayinka A. Oyewale (2015). Complications of Allogeneic Blood Transfusion: Current Approach to Diagnosis and Management. International Blood Research & Reviews, 3(4), 135-151. https://europub.co.uk/articles/-A-242477