Compositions of Thunbergia grandiflora Leaf and Root Essential Oils
Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2017, Vol 15, Issue 1
Abstract
Fresh samples of leaves and roots of Thunbergia grandiflora were collected from forest- reserved area, Ibadan, Nigeria for extraction of their volatile oils. Hydro-distillation method was used in an all-glass Clevenger apparatus designed to British pharmacopeia specifications. It gave yields of 0.09% and 0.10% respectively. The oils were analyzed using gas chromatography [GC], gas chromatography-mass spectrometry [GC-MS] in University of Botswana. A total of thirty-eight compounds were identified in the leaf and root essential oils, twenty-seven compounds were identified in leaf oil, which account for 98.13% of it while seventeen identified compounds are responsible for 73.98% of root oil. Most abundant compounds in leaf oil are α-3-octanol (45.96%), 3,7 dimethyl 1,6-octadien-3-ol (13.22%) and 2- methoxy-3-(2-propenyl) phenol (8.36%). Dominant compounds in root oil are methyl salicylate (44.80%), 2,21,5,51-tetramethyl-1,11 - biphenyl (5.05%) and i-propyl hexadecanoate (2.87%). leaf oil is dominated by following classes of compounds (%); alcohols (68.58), carboxylic acid (4.01), aldehydes (12.90), ketones (5.18), esters (2.62), aromatics (0.66) and also sulphurates (0.45). Classes of compounds in root oil are esters (47.67), alcohols (2.64), carboxylic acids (0.55), aldehydes (7.69), sulphurates (1.61), aromatics (5.05) and alkane (5.02). The two oils contain alcohols and esters in good amounts. Our results indicate that alcohols, esters and aldehydes dominate Thunbergia grandiflora essential oils. We present important compounds in the leaf and root essential oils of Thunbergia grandiflora, which have not been reported earlier in literature.
Authors and Affiliations
Kingsley Adibe Mbachu, Dorcas Olufunke Moronkola
Keywords
Related Articles
- EP ID EP313204
- DOI 10.9734/JAMPS/2017/35836
- Views 104
- Downloads 0
Development and Validation of Stability Indicating UFLC Method for the Estimation of Anti-spasmodic Drug - Valethamate Bromide
A stability indicating Ultra-Fast Liquid Chromatography (UFLC) method has been developed to estimate valethamate bromide (V&B) in tablet dosage forms and to separate analyte from other degradants and to carryout forced d...
The Effect of Co-administered Drugs and Food on the Absorption of Artemether–Lumefantrine Tablet
The physicochemical properties of drugs, their dosage forms and routes of administration affect the rate and extent of drug absorption. Oral administration of drugs presents with variable absorption profiles due to multi...
In utero Exposure to Oxcarbazepine Causes Congenital Anomalies in Albino Rat Fetuses
Aims: Oxcarbazepine (OXC) is a newer antiepileptic agent that has recently become increasingly used either as monotherapy or as an adjunct to other AEDs in adults, adolescents, and children with partial epilepsy. Our aim...
Detection of and Adjustment for Multiple Unmeasured Confounding Variables in Logistic Regression by Bayesian Structural Equation Modeling
Aim: To compare the bias magnitude between logistic regression and Bayesian structural equation modeling (SEM) in a small sample with strong unmeasured confounding from two correlated latent variables. Study Design: Stat...
Experimental Evaluation of Analgesic and Antioxidant Effects of Hydromethanolic Extract of Dioscorea dumetorum Tuber
Aims: The hydromethanolic extract of D. dumetorum was evaluated for antinociceptive and antioxidant activities to validate its uses in traditional medicine for these purposes. Methods: The antioxidant activity of D. dume...