COMPUTER AIDED DRUG DESIGN: A COMPUTATIONAL METHOD FOR DRUG DISCOVERY AND DEVELOPMENT
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2019, Vol 6, Issue 3
Abstract
Computer aided drug design (CADD) or insilico design is the application of computational or computer modeling in drug design. Drug is a biomolecule that can bind to a target receptor resulting to pharmacological response. The purpose of drug design is to predict the binding ability and strength at which a molecule can bind to target of an interest. Computer aided drug design may be applied at stages such as hit identification using virtual screening, hit-to-lead optimization of affinity and selectivity and lead optimization. Utilizing computational techniques have given rise to remarkable progress in drug discovery.
Authors and Affiliations
Ike O. C.
Keywords
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