Concentration Polarization of Ox-LDL and Its Effect on Cell Proliferation and Apoptosis in Human Endothelial Cells
Journal Title: Journal of Cardiology and Cardiovascular Medicine - Year 2016, Vol 1, Issue 1
Abstract
Background: Flow-dependent concentration polarization of native LDL is important in the localization of atherogenesis. However, ox-LDL plays a more important role than n-LDL in atherogenesis by inducing cell proliferation and apoptosis. We hypothesized that concentration polarization of ox-LDL may adversely affect vascular beds due to its toxicity to endothelial cell (EC) lining.
Authors and Affiliations
S Liu, JL Mehta, Y Fan, X Deng, Z Ding
Keywords
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- EP ID EP541222
- DOI 10.29328/journal.jccm.1001003
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