Concise and Efficient Total Syntheses of Virenamides A and D
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2013, Vol 4, Issue 3
Abstract
Concise total syntheses of linear thiazole-containing peptides virenamides A (1) and D (4), isolated from Australian ascidian Diplosoma virens have been accomplished from Boc-L-valine (6) in 7 steps. A cyclization between thioamide and bromoacetaldehyde was applied to form thiazole ring as a key step.
Authors and Affiliations
Gan Haifeng, Chen Zhengbang, Fang Zheng, Guo Kai
Keywords
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- EP ID EP652534
- DOI 10.24297/jac.v4i3.945
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