Concomitant aortic regurgitation is a predictor of outcome after surgical aortic valve replacement in patients with severe aortic stenosis

Journal Title: International Journal of Medical Science and Public Health - Year 2017, Vol 6, Issue 2

Abstract

Background: Concomitant aortic regurgitation (AR) might worsen the prognosis of severe aortic stenosis (AS). But the prognostic value of concomitant AR in patients operated for severe AS is not addressed. Objective: The aim of this study was to assess the impact and association of presence and severity of concomitant AR in patients operated for severe AS on long-term left ventricular (LV) function, functional capacity, and mortality. Materials and Methods: Study group consisted of 200 patients operated due to severe AS retrospectively. The patients were divided into AS group (100 patients with AS without AR or with mild AR) and AS+AR group (100 patients with AS and moderate, severe or very severe AR). Follow-up included a clinical examination and echocardiography 5–30 months after AVR. Result: Patients in AS group had improved symptoms than AS+AR group. The patients with postoperative follow-up in AS group had lower LV volume indices than patients in AS+AR which was statistically significant(AS group; LVEDVi - 67±9.1, LVESVi - 22±7.2 compare to AS+AR group; LVEDVi - 84±21.3, LVESVi - 34±11, p-value< 0.05). Postoperative mean LVEF was 61±11 and 58±12 in AS and AS+AR group, respectively. Conclusion: Our study indicates that the preoperative presence and severity of concomitant AR has an impact on the outcome after aortic valve replacement for the patients having severe aortic stenosis symptoms on the basis of symptoms,LV remodeling, systolic and diastolic function.

Authors and Affiliations

Prashant Mishra, Chandan Kumar Ray Mohapatra, Jayant V Khandekar, Chaitanya Raut, Harsh S Seth, Ganesh Kumar K Ammannaya, Jaskaran Singh, Vaibhav Shah

Keywords

Related Articles

Socio-demographic profile of hanging cases at New Civil Hospital, Surat

Background: Violent asphyxial deaths are one of the important causes of death nowadays. For reasons not known to others, victims end their life by committing suicide. Hanging is one of the preferred mode of committi...

Langerhans cell histiocytosis involving bilateral temporal bones in infant patient: a case report &nbsp;

&nbsp;Langerhans’ cell histiocytosis (LCH) is a rare pediatric disease of unknown etiology. The mastoid and skull base are common sites of involvement in LDH. We present a case of bilateral langerhans histiocytosis in 9...

Gender preference and factors affecting gender preference of mothers attending antenatal clinic of Agartala government medical college

Background: Consecutive decline in sex ratio of our country signals an impending crisis. Gender preference of women may have a role in determining sex ratio. Aims &amp; Objective: To study the gender preference and...

Knowledge, beliefs, and practices regarding malaria in urban setting of East Khasi Hills district, Meghalaya

Background: Malaria is still a leading public health problem in the northeastern regions of India. Besides mosquitogenic conditions in tribal areas, poor knowledge and attitude toward the disease is also one of the r...

Incidence of various clinico-morphological variants of cutaneous tuberculosis and its drug susceptibility pattern-Delhi based study

Background: Tuberculosis was declared global emergency in year 1993. The global spread of the disease is complicated by the ubiquitous appearance of drug-resistant strains, and particularly multidrug-resistant (MDR) stra...

Download PDF file
  • EP ID EP300732
  • DOI 10.5455/ijmsph.2017.06082016607
  • Views 46
  • Downloads 0

How To Cite

Prashant Mishra, Chandan Kumar Ray Mohapatra, Jayant V Khandekar, Chaitanya Raut, Harsh S Seth, Ganesh Kumar K Ammannaya, Jaskaran Singh, Vaibhav Shah (2017). Concomitant aortic regurgitation is a predictor of outcome after surgical aortic valve replacement in patients with severe aortic stenosis. International Journal of Medical Science and Public Health, 6(2), 314-317. https://europub.co.uk/articles/-A-300732