Concomitant Pregabalin and Tramadol Hydrochloride/Acetaminophen Formulation Relieved Neuropathic Itch of Gingiva: A Case Report

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12

Abstract

Neuropathic itch of the gingiva is seldom seen in clinical situations, and most clinicians, including dental practitioners, do not have a way to deal with this condition. We report a case of neuropathic itch of gingiva that was successfully treated with concomitant pregabalin (50 mg 2×/day) and tramadol hydrochloride/acetaminophen (T/A: 37.5 mg/325 mg 1×/day) formulation. The 57-year-old Japanese female patient visited our hospital due to an itchy sensation of the right lower gingiva. The concomitant pregabalin and T/A formulation remarkably relieved the patient’s itch; her score on a visual analogue scale representing itchy intensity was remarkably decreased at 2 weeks after the treatment initiation. The concomitant medication also improved her health-related quality of life (HRQoL) scores based on the Japanese version of the ShortForm 8 (SF-8) health survey. Significant adverse events did not occur. This concomitant medication may thus be useful for the treatment of neuropathic itch of gingiva.

Authors and Affiliations

Yukihiro Momota, Keiko Aota, Hideyuki Takano, Koichi Kani, Masayuki Azuma

Keywords

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  • EP ID EP421647
  • DOI 10.9790/0853-1712036871.
  • Views 56
  • Downloads 0

How To Cite

Yukihiro Momota, Keiko Aota, Hideyuki Takano, Koichi Kani, Masayuki Azuma (2018). Concomitant Pregabalin and Tramadol Hydrochloride/Acetaminophen Formulation Relieved Neuropathic Itch of Gingiva: A Case Report. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 17(12), 68-71. https://europub.co.uk/articles/-A-421647