Concurrent Chemoirradiation in Elderly Head and Neck Cancer Patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Cancer and its treatment can affect the overall life expectancy as well as the active life expectancy and function of older patients. H and N cancers are the leading cancer in elderly population. The present study evaluated the pattern of tolerance and response to treatment in elderly(>65 years) H & N cancer patients. A total of 30 elderly patients of age >65 years of head and neck cancer were treated with concurrent chemoirradiation. Of the 30 patients planned for concurrent chemoirradiation, only 22 patients(73.3%) were able to complete the prescribed treatment. 2 patients were not able to finish the course of chemoirradiation. Both the patients developed grade 4 thrombocytopenia and neutropenia during the treatment course. 6 patients(20%) expired during the treatment course. All the patients expired because of aspiration pneumonia. 5 patients received <3 cycles of chemotherapy. This study concluded that Concurrent chemoRadiation therapy is well tolerated in elderly patients with minor toxicities.With a thorough risk benefit assessment patients can be offered a curative treatment.
Authors and Affiliations
Manikumar S, Hasib A G, Almeida V G, Athiyamaan M S, Sandesh Rb, Sharaschandra S
Comparison Between Excision With Simple Primary Closure And Limberg’s Flap Reconstruction In Pilonidal Sinus Disease
Introduction: The ideal treatment for pilonidal sinus should ensure low pain, short hospitalization period, low risk of complication, rapid return to normal activities, and should have a low recurrence rate. The aim of t...
Gamma Glutamyl Transferase As A Diagnostic Marker in Alcohol Induced Hepatotoxicity
Abstract: Liver disease is a general term for any damage that reduces the functioning of the liver. As a large organ the liver shares with many other abilities to perform its functions with extensive reserve capacity. Ga...
A Comparative Study Of Efficacy And Safety Of Intravenous Ferric Carboxymaltose Versus Intravenous Iron Sucrose In The Treatment Of Iron Deficiency Anaemia Of Pregnancy
.
Evaluation Of Results In Fracture Both Bones Forearm Treated With Dynamic Compression Plating. A 2 Year Follow-up Study
.
Shear Bond Strength of Composite Resin on Exposed Dentine Surface Using Vth Generation Bonding Agent With And Without Hybrid Layer –An in Vitro Study & SEM Analysis
The purpose of this study is to remove the collagen layer left back after acid conditioning with 5% sodium hypochlorite and subsequent bonding onto partially demineralised dentine thereby producing more durable adhesion...