Congenital Chloride Diarrhoea
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 2
Abstract
Congenital chloride losing diarrhea (CLD) is a medical emergency case in pediatrics. It is a rare genetic disorder caused due to mutation of chromosome 7.It is commonly seen in Saudi Arabic countries ,It is seen in early neonates with features of absence of meconium,“urine like diarrhea” ,antennal finding shows hydraminous child in fetus ,fecal chloride concentration is more than 90mmol/l. The main treatment for CLD is continuous lifelong replacement of faecal loss water ,NaCl and KCl by salt substitution therapy, use of proton pump inhibitor etc ,with early diagnosis long term outcome is favourable .
Authors and Affiliations
Dr. Nandita Basak
Keywords
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