CONGENITAL ICHTHYOSIS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 8
Abstract
The congenital ichthyosis is genetic defect. The main reason of congenital ichthyosis is defect in metabolism of keratin(protein present in skin). The alpha-keratin is converted into beta-keratin. Keratinocytes are the cells present in outer layer of skin. Congenital ichthyosis also called as harlequin fetus. In this disorder newborn babies skin is dry and they have fish like scales. DNA base analysis for prenatal testing is reliable and conclusive for diagnostic purpose of Congenital Ichthyosis. Skin of newborn should be kept soft by using petroleum based creams. Keratolytic agents like alpha hydroxy acid or urea preparations are usually used in older children.
Authors and Affiliations
Mahadev Govindrao Tate
Keywords
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