CONGLOMERATION OF POLY HERBAL DRUGS AS LEHYA FORMULATION HAVING ANTIOXIDANT ACTIVITY WITH EXTRACTS OF ANNONA SQUAMOSA, CASSIA FISTULA AND ILLICIUM VERUM
Journal Title: World Journal of Advance Healthcare Research - Year 2018, Vol 2, Issue 3
Abstract
Herbal medicine also called Botanical medicine or phyto medicine refers to using a plant parts such as seeds, berries, roots, leaves, bark, or flowers for medicinal purposes. Recently, World Health Organization estimated that 80% of people worldwide rely on herbal medicines. Now a day, Digoxin is a purified cardiac glycoside that is extracted from the foxglove plant, Digitalis lanata. Digoxin is widely used in the treatment of various heart conditions, namely atrial fibrillation and atrial flutter. Elements that are more reluctant to lose electrons are not easily oxidized. Nonmetals like nitrogen, oxygen, and chlorine are not easily oxidized. Antioxidants block the process of oxidation by neutralizing free radicals. The intensity of the yellow colour formed was measured at 412 nm against a reagent blank. Ascorbic acid and gallic acid were used as standards. The percentage of inhibition was determined by comparing test with standard. The polyherbal formulation in the form of Lehya meant for antioxidant activity is prepared by using suitable plants reported to possess antioxidant properties such as leaves of Annona squamosa, leaves of Cassia fistula and fruits of Illicium verum. The preparation for standardization included loss on drying, total ash, acid insoluble ash, alcohol soluble extractive value, water soluble extractive value and PH was estimated. Formulated poly herbal lehya was proved to show pronounced in-vitro antioxidant activity and its percentage inhibition was at 200μg concentration was found to be 95.42 of DPPH inhibition, and 69.49 of Nitric oxide.
Authors and Affiliations
Shaik Kareemulla
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