Consumption of Aloe vera Mucilage Attenuates Plasma Oxidative Stress and Dyslipidemia in Type 2 Diabetic Rats

Journal Title: Global Journal of Biotechnology and Biomaterial Science - Year 2015, Vol 1, Issue 1

Abstract

This study found that Aloe vera mucilage administration significantly improved biological parameters including lipids composition and oxidative stress in type 2 diabetic rats. Because the mRNA levels of lipogenic genes were significantly down-regulated (P<0.01) by the intervention of A. vera mucilage, this improvement of these biological parameters may be caused, at least in part, by the regulation of hepatic genes that are involved in lipids metabolism, thus resulting in an increase of cholesterol clearance and β-oxidation as well as a reduction of hepatic lipogenesis. The results in this study might provide a further beneficial effect of A. vera mucilage in the possible management of dyslipidemia-related diseases.

Authors and Affiliations

Zhou ZhongKai, Ren Xiaochong

Keywords

Related Articles

Ruta graveolens Protects Against Isoniazid/Rifampicin-Induced Nephrotoxicity through Modulation of Oxidative Stress and Inflammation

Background and Aim: Drug-induced nephrotoxicity is a renal dyfunction that arises as a result of exposure to nephrotoxic drugs. Anti-tuberculosis therapy can cause nephrotoxicity and permanent kidney damage. The current...

Important Factors Influencing Protein Crystallization

The solution of crystallization problem was introduced around twenty years ago, with the introduction of crystallization screening methods. Here reported some of the factors which affect protein crystallization, solubili...

A Protocol for the Computational Design of High Affinity Molecularly Imprinted Polymer Synthetic Receptors

Molecularly imprinted polymer (MIP) nanoparticles, commonly referred to as ‘plastic antibodies’ or synthetic receptors, are polymeric materials with strong affinity and selectivity for a particular chemical target. MIPs...

MicroRNAs in Oncology

MicroRNAs (miRNAs) are a family of short non-coding RNA molecules which contain about 18-24 nucleotides. miRNAs play significant regulatory roles in biological processes (cell proliferation, differentiation, survival and...

Nano-Technological Approaches to Improve the Efficiency of Bio-Assays

One of the biggest issues in today's healthcare industry is to find a very fast yet effective diagnostic platform, which is suitable for our busy lifestyle without compromising the detection efficiency. The major require...

Download PDF file
  • EP ID EP555749
  • DOI 10.17352/gjbbs.000001
  • Views 37
  • Downloads 0

How To Cite

Zhou ZhongKai, Ren Xiaochong (2015). Consumption of Aloe vera Mucilage Attenuates Plasma Oxidative Stress and Dyslipidemia in Type 2 Diabetic Rats. Global Journal of Biotechnology and Biomaterial Science, 1(1), 1-3. https://europub.co.uk/articles/-A-555749