Consumption of Aloe vera Mucilage Attenuates Plasma Oxidative Stress and Dyslipidemia in Type 2 Diabetic Rats
Journal Title: Global Journal of Biotechnology and Biomaterial Science - Year 2015, Vol 1, Issue 1
Abstract
This study found that Aloe vera mucilage administration significantly improved biological parameters including lipids composition and oxidative stress in type 2 diabetic rats. Because the mRNA levels of lipogenic genes were significantly down-regulated (P<0.01) by the intervention of A. vera mucilage, this improvement of these biological parameters may be caused, at least in part, by the regulation of hepatic genes that are involved in lipids metabolism, thus resulting in an increase of cholesterol clearance and β-oxidation as well as a reduction of hepatic lipogenesis. The results in this study might provide a further beneficial effect of A. vera mucilage in the possible management of dyslipidemia-related diseases.
Authors and Affiliations
Zhou ZhongKai, Ren Xiaochong
Keywords
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- EP ID EP555749
- DOI 10.17352/gjbbs.000001
- Views 45
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