Consumption of Different Forms of Palm Oil Formulated Diets Has No Effect On Learning and Memory in Mice
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 8
Abstract
The consumption of different forms of palm oil has been reported to have an enormous systemic effect; this study was aimed at evaluating the effects of different forms of palm oil; Fresh and thermoxidized palm oil on learning and memory in CD1 mice. Twenty seven (27) mice were used for this study. There were arbitrarily assigned into three (3) groups, Control, Fresh palm oil (FPO) fed and Thermoxized palm oil (TPO) fed groups, n=9. The control group received normal rat feed. The FPO-fed and TPO-fed groups received fresh palm oil diet and thermoxidized palm oil diets respectively. All animals had access to water ad libitum. The feeding lasted for 14 weeks. At the termination of the feeding period, learning and memory was assessed using the Morrice water maze (MWM). The results obtained showed that there was no significant difference in the swim latencies in both acquisition and reversal training, also, no significant difference was observed in the quadrant duration during the probe trial, and the visible platform task. This is indicative of equal learning ability for all the animals across all the experimental groups. Long term consumption of FPO and TPO has no significant effect on visuospatial learning and memory. Keywords: Fresh palm oil, Thermoxidized palm oil, Learning and memory, Morris water maze.
Authors and Affiliations
Mfem CC, Ofutet EO, Antai AB, Osim EE
Keywords
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