Consumption of elicited soybean sprout flour increases calcium level in serum of ovariectomized rats

Journal Title: Universa Medicina - Year 2017, Vol 36, Issue 2

Abstract

Background The decline in estrogens could lead to an imbalance of bone formation and absorption as well as bone mineralization. Phytoestrogens are known to have the potential to maintain bone health. Calcium and phosphorus are essential components for bone mineralization. This study aimed to investigate the effect of soybean sprout flour consumption on serum calcium and phosphorus levels in ovariectomized rats. Methods A randomized post-test-only control group design involving 25 female Sprague-Dawley rats aged 2 months, which were divided into five groups: (i) normal controls on standard feed diet AIN-93 (C-N), (ii) ovariectomy controls on standard feed diet (OVX -N); (iii) ovariectomized rats on standard feed diet + ethinylestradiol (OVX -E), (iv) ovariectomized rats on standard feed diet + soybean flour (OVX -S); (v) ovariectomized rats on standard feed diet + soybean sprout flour (OVX -SS). The rats were treated for 6 weeks, then on the last day of treatment blood sampling was conducted. Analysis of calcium and phosphorus in serum was performed using the Arsenazo III photometric method. Data were analyzed using one-way Anova. Results Mean serum calcium level was highest in the OVX-SS group (12.59 mg/dL ± 1.32), while mean serum phosphorus level was highest in the C-N group (1.708 mg/dL ± 0.28). Soybean sprout flour consumption had a significant effect on serum calcium levels (p=0.019), yet it had no effect on body weight and serum phosphorus levels of the rats. Conclusion Consumption of soybean sprout flour could positively affect serum calcium levels in rats.

Authors and Affiliations

Siti Aminah, Suparmo Suparmo, Sri Naruki, Hastari Wuryastuty

Keywords

Related Articles

Short-term aerobic exercise does not change kidney function in students of Nnamdi Azikiwe University, Nigeria

Background Exercise has been known to have beneficial effects on human health. The kidneys play an important role in regulating acid-base and water-electrolyte balance disturbances induced by exercise. The objective of t...

Age-related changes of malondialdehyde, body weight and organ weight in male mice

Introduction Aging is characterized by gradual impairment in all physiological functions. Increases in free radicals and changes in organ morphology occur with aging. The purpose of this study was to determine age-relate...

Cervical consistency index is a valid predictor of preterm birth in low-risk pregnant women

Background Preterm birth (PTB) remains a global problem associated with perinatal morbidity, including low birth weight, growth retardation and irreversible damage to the nervous system. The objective of this study was t...

Performance of osteoporosis self-assessment tool in detecting low bone mineral density in menopausal women

Background The osteoporosis self-assessment tool (OST) is a simple screening tool to assess risk of osteoporosis and to select high risk women for dual-energy x-ray absorptiometry (DXA) examination. This study aimed to e...

Hormonal contraception increases risk of breast tumor based on clinical breast examination among adult women

Background In Indonesia, cancer prevalence according to the Basic Health Research 2013 was 1.4 per 1000 inhabitants and the most common cancer in hospitalized patients in 2010 was breast cancer (28.7%). Hormonal contrace...

Download PDF file
  • EP ID EP376431
  • DOI 10.18051/UnivMed.2017.v36.94-101
  • Views 297
  • Downloads 0

How To Cite

Siti Aminah, Suparmo Suparmo, Sri Naruki, Hastari Wuryastuty (2017). Consumption of elicited soybean sprout flour increases calcium level in serum of ovariectomized rats. Universa Medicina, 36(2), 94-101. https://europub.co.uk/articles/-A-376431