Continuous Versus Bolus Dosing of Furosemide in the Treatment of Patients with Acute Decompensated Heart Failure
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 9
Abstract
Abstract:In cases of acute decompensated heart failure, Loop diuretics are important modality of treatment, but there are few study to guide there use.Patients admitted with ADHF were randomized into two groups - continuous infusion and bolus therapy group with furosemide. Following are considered as the end points, negative fluid balance, duration of hospital stay, trend of serum electrolytes and one month clinical outcome (Death and hospital readmission).Total 50 patients were included in the study (25 in each group). We noticed that there was significant diuresis in the first 24 hour and shorter hospital stay in bolus group. There was no significant difference in serum sodium and potassium levels and hospital readmission. There was no significant difference in the renal parameters.Both continuous infusion and bolus dose diuretic modality of treatment have equal role in the management of ADHF with no significant difference in the renal function and electrolytes level. Bolus dose diuretic strategy has been associated with shorter hospital stay and rapid improvement in clinical symptoms so, it might be effective diuretic strategy. Keywords:Heart failure, diuretics, bolus, infusion, furosemide
Authors and Affiliations
Prashanth Kumar Malkiwodeyar, Narendra Hiregoudar, Durgaprasad Kabade, Ishwar Hasabi
Keywords
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