Contraceptive Vaccines
Journal Title: Актуальна інфектологія - Year 2014, Vol 2, Issue 1
Abstract
Researches to develop vaccines with contraceptive effect are being carried out since the 1920s. Since 1972, the contraceptive vaccines are one of the priority programs of the World Health Organization (WHO Special Programme of Research, Development and Research Training in Human Reproduction). Rockefeller Foundation participates in implementing the program. Openly declared objective of creating such vaccines — the regulation of the population in the Third World countries. There are currently three main directions of contraceptive vaccine design: 1) vaccines targeted at blocking the production of gametes; 2) impairing their function; 3) violating the fertilization process. Contraceptive vaccines for more than 10 years are widely used to reduce fertility and castration of wild and domestic animals. In the commercial realization there are veterinary vaccines Equity®, Improvac®, GonaCon®, Repro-BLOC (based on gonadotropin-releasing hormone); SpayVac™ and IVT-PZP® (based on zona pellucida antigens). Clinical studies have shown effective contraceptive action (in women) of vaccines, in which human chorionic gonadotropin is used as an antigen. At the same time, there are found the side effects of such vaccines: for vaccines containing gonadotropin-releasing hormone and luteinizing hormone as antigenic components — castration, impotence; for vaccines containing follicle stimulating hormone — oligospermia; zona pellucida antigens — irreversible oophoritis. This paper discusses approaches to detection of sterilizing components in vaccines intended for mass prevention of infectious diseases, not reported by manufacturers, and the consequences of their use. Hidden use of contraceptive vaccines, which already took place, can be detected: 1) by the presence of antibodies to their antigenic components (in unvaccinated by contraceptive vaccines people such antibodies do not exist, except infertility cases); 2) by change in the hormonal levels of the vaccinated patients; 3) by malfunction and histopathological changes in the reproductive organs.
Authors and Affiliations
M. V. Supotnitsky
Keywords
Related Articles
- EP ID EP224073
- DOI -
- Views 150
- Downloads 0
Case of Lyme borreliosis in a child
Lyme borreliosis (synonym: Lyme disease) is an infectious transmissible natural focal disease, the causative agents of which are spirochetes, and carriers — ixodid ticks. The first cases of Lyme borreliosis in Ukraine ar...
Health-Related Quality of Life in Chronic HCV Patients, Who Don’t Know About Their Disease
The purpose of the study — to determine how much the awareness of HCV patients about their disease affects health-related quality of life. Indices of health-related quality of life were studied in 893 people who were div...
Herbal enterosorbent effect in newly diagnosed destructive pulmonary tuberculosis management
Background. The search for pathogenetic therapeutic methods aimed at improving the immune status of a patient with tuberculosis without prescribing of specific immunomodulators is still relevant. This became the basis fo...
Clinical features of nervous system disorders in patients with EBV as monoinfection and in association with other herpes viruses in their reactivation and persistence
We have examined 48 patients with nervous system disorders caused by Epstein — Barr virus (EBV) as monoinfection or in association with other herpes viruses during their reactivation (n = 34) or persistence (n = 14). Wit...
Effect of sodium selenite on thyroid gland functioning and efficacy of chemotherapy in tuberculosis patients with a concomitant diabetes mellitus and autoimmune thyroiditis
In 40 tuberculosis patients with diabetes mellitus and autoimmune thyroiditis ultrasonic research of thyroid structure and measurement of levels of free thyroxine, thyroid stimulating hormone, antibodies to thyroglobulin...