CONTROL OF THE GENOTOXICITY LEVEL OF CERTAIN MYCOTOXINS BY A FIBER OPTICAL SOS-TYPE BIOSENSOR
Journal Title: World Journal of Engineering Research and Technology - Year 2018, Vol 4, Issue 6
Abstract
In addition to their well-known general toxicity, mycotoxins have also been found to often exert genotoxicity. In turn, not only the presence of the mycotoxins is required to be determined, but such DNA-damaging effects by these substances are also needed to be detected in routine monitoring of mycotoxin. The main purpose of this article is to demonstrate the utility of a proposed special fiber optical SOS-chromotest type biosensor, based on the SOS-lux assay in recombinant Escherichia coli cells, in rapid measurement of the genotoxicity level of mycotoxins. The optrode-based fiber optic biosensor and its main operating conditions for such express analysis have been worked out, moreover, its efficacy in the determination of the effects of certain investigated mycotoxins e.g.,T2 mycotoxin, patulin, aflatoxin B2, zearalenone and ochratoxin on the genetic apparatus applied and their activation of the operon of the reparative genes is reported. The genotoxicity of the mycotoxins studied fell in the same range, with genotoxicity order: T2 mycotoxin > aflatoxin B2 > patulin >> ochratoxin > zearalenone.
Authors and Affiliations
N. F. Starodub
Keywords
Related Articles
- EP ID EP664818
- DOI -
- Views 147
- Downloads 0
STUDY OF HIGH PERFORMANCE CONCRETE USING NANOSILICA AS AN ADMIXTURE-A REVIEW
High performance concrete(HPC) use in present days is increasing as conventional concrete does not meets the requirement. Hence it is necessary to develop HPC. For the production of HPC, the pozzolanic materials (silica...
COMPARATIVE ANALYSIS OF FACE, IRIS AND FINGERPRINT RECOGNITION SYSTEMS
Biometrics is the science of establishing the identity of an individual based on the physical chemical or behavioural attributes of the person. Among these face, iris and fingerprint have remained the most researched and...
PERFORMANCE EVALUATION OF 3-HOP RELAYING PROTOCOLS FOR COGNITIVE RADIO NETWORKS
Cognitive radio network is an emerging field in communication and are giving benefits in various areas. It provides efficient utilization of frequency spectrum and spares bandwidth for other applications. There are vario...
A REVIEW ON DOUBLE GATE MOSFET
According to Moore's law number of transistors in a given area double in a period of around 18 months. Thus size of the devices need to be reduced continuously. With continuous down scaling of single gate MOSFET it resul...
A SOCIO-ECONOMIC ANALYSIS ON ENVIRONMENTAL HEALTH ISSUES IN THE HAMBANTOTA DISTRICT OF SRI LANKA
This article is based on a study conducted to identify causes and impacts of environmental health issues in the Hambantota district which is situated in the Dry Zone of the southern province of Sri Lanka. The analysis ha...