Convenient Method for the Synthesis of 1,2,4-Substituted Dithiazoles
Journal Title: Haya: The Saudi Journal of Life Sciences - Year 2016, Vol 1, Issue 4
Abstract
Abstract: A simple, novel and suitable method has been developed for the one step synthesis series of 3-substitutedimino-5-[2-isobutoxy-5-(4-methyl-5-carboxy-1,3-thiazo-2-yl)-phenylformamidino]-amino-1,2,4-dithiazoles(VIa-f)was carried out by oxidative cyclisation of 2-(3-substituted-2,4-dithiobiureto-formamidino-4-isobutoxyphenyl)-4-methyl-5-carboxy-1,3-thiazoles (Va-f) by making use of liquid bromine in chloroform medium as an oxidative cyclising agent. Keywords: Dithiazoles, Synthesis, an oxidative cyclising agent.
Authors and Affiliations
D. T. Tayade, A. S. Shendge
Keywords
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