Convenient Synthesis of Some New Bi-heterocycles conataining 3-Aminoquinazolin-4(3H)-one and 1,2,4-Triazole moieties
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 10, Issue 9
Abstract
Dicarboxylic acids, thiosemicarbazides and methylanthranilate reacted to give methyl-2-(3-(5-mercapto-4-s-1,2,4-triazol-3-yl)-3-oxoalkylamino)benzoates 4. The laters, cyclized with hydrazine hydrate to give 3-amino-2-((5-mercapto-4 substitued-1,2,4-triazol-3-yl)alkyl)quinazolin-4(3H)-ones 5 which expected to have biological effects.
Authors and Affiliations
Yasser H. Zaki, Mahmoud A. Mohamed
Keywords
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- EP ID EP652777
- DOI 10.24297/jac.v10i9.876
- Views 148
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