Corneal ulcer: A prospective clinical and microbiological study
Journal Title: International Journal of Medical Science and Public Health - Year 2014, Vol 3, Issue 11
Abstract
Background: It is important to study the epidemiologic features and predisposing factors of corneal ulcer and subsequently to find out its causative agents and their antimicrobial susceptibility patterns in a given community, climate and culture. Aims & Objective s : This prospective study of 100 cases of corneal ulcer was undertaken to bring out the bacterial and fungal prevalence among different age groups. Materials and Methods: Corneal scrapings were collected from all patients. One cor neal swab and three corneal scrapings were collected. Direct examination of samples was done by potassium hydroxide wet mount and gram stained smear and then inoculated onto blood agar, MacConkey’s agar and Saboraud's dextrose agar media. Identification of fungal growth finally was done based on its macroscopic and microscopic features. Bacterial colonies were identified by Gram staining and standard biochemical tests and antimicrobial susceptibility testing was carried out for each bacterial isolate. Resul ts: Out of total 100 specimens of corneal ulcer, only 55% cases were found to be culture positive in which bacteria were more frequently isolated than fungi. Staphylococcus aureus and Aspergillus spp were the most frequent bacterium and fungus. The inciden ce was higher in males and in age group of >40 - 60 years. While S. aureus was found to be most sensitive to vancomycin, Staphylococcus epidermis was most sensitive to cefazoline . Conclusion: S. aureus and Aspergillus spp were the most common isolate to be associated with corneal ulcer, and the incidence was higher in rural population, especially farmers, who were constantly exposed to vegetative matter
Authors and Affiliations
Shashi Gandhi, DK Shakya, KP Ranjan, Sonika Bansal
Keywords
Related Articles
- EP ID EP153511
- DOI 10.5455/ijm sph. 2014. 0 3 0 8 2014 2
- Views 91
- Downloads 0
Microbial profile and antibiotic susceptibility pattern of orthopedic infections in a tertiary care hospital: A study from South India
Background: Orthopedic wound infections are one of the most important causes of morbidity and are difficult to treat. Changes in pathogenic microbial flora and the emergence of bacterial resistance are another problem in...
A study of the effects of HIV infection and ART treatment on the serum lipid profile of HIV/AIDS patients attending the Nylon District Hospital, Douala, Cameroon
Background: Antiretroviral therapy (ART) has been shown to substantially reduce morbidity and mortality in human immunodeficiency virus (HIV) seropositive patients. However, long-term management of patients on ART ma...
Pattern of rates of exclusive breastfeeding in the Niger Delta region of Nigeria
Background: The promotion of exclusive breastfeeding has the potential to make a major contribution to the achievement of the child Millennium Development Goals. Objective: The aim of this study was to document t...
How to adjust the strategy of radiopathologic teaching to achieve the learning outcomes?
Background: The integrated‑based education must pay attention to the beneficiaries, in whom our learning outcomes would be achieved. For establishing any curriculum for integrated‑based medical schools, one must be aware...
Effect of a health education program on cancer awareness among college students: Responding to the challenges of cancer control in India
Background: Cancer is a major public health problem worldwide. One of the most cost effective strategies identified for better cancer control is emphasis on health education. Aims & Objective: T...