Correlating Upper GI Symptoms and Endoscopic Findings with H Pylori Positivity – A Rural Tertiary Care Perspective
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 10
Abstract
Introduction: H pylori infection is associated with wide spectrum of neoplastic and non-neoplastic lesions and commonly presents as dyspepsia. Upper gastrointestinal endoscopy not only helps to differentiate between organic and functional dyspepsia, but also helps in the diagnosis of H pylori infection. In this study we aim to assess the prevalence of helicobacter pylori associated gastrointestinal diseases using rapid urease test (RUT) in patients undergoing endoscopy with upper GI symptoms in rural Kerala. Materials and Methods: This observational cross sectional descriptive study was done in the Department of Gastroenterology at DM Wayanad institute of medical sciences, which is a tertiary care setup in rural Kerala. 510 patients, who underwent gastrointestinal endoscopy for various upper GI symptoms were included in the study. After applying exclusion criteria, 479 patients with demographic details, upper GI symptoms list, endoscopic findings and H pylori results formed the crux of the study. Results: Among 479 patients evaluated, males (58%) were predominant.248 (51.7%) of the 479 patients were H pylori positive. Dyspepsia (66.5%) was the commonest symptom amongst the H pylori positive patients. Gastritis was the commonest endoscopic finding followed by esophagitis and duodenal ulcer both in the general study group and in the H pylori positive group. Amongst 8 patients with carcinoma of stomach, 7 patients were positive for H pylori infection and this association was statistically significant. Conclusion: Dyspepsia as a symptom has great social and economic impact and is the commonest symptom presenting to the physician. Being a developing country with limited resources and its ever increasing elderly population and high prevalence of H pylori and dyspeptic symptoms, larger study to frame appropriate guidelines for endoscopy and empirical treatment of dyspepsia is desired
Authors and Affiliations
Shuba Srinivasan
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