Correlation and Predictive Value of the FDG uptake within Primary Mass in Non-small Cell Lung Carcinoma and Incidence of Distal Metastases
Journal Title: ​International Journal of Contemporary Medicine surgery and Radiology - Year 2018, Vol 3, Issue 3
Abstract
Introduction: Identification of tumour anatomic and functional features may allow us a better understanding of cancer dissemination. Here, we investigated how 18-Fluorine -Fluoro-2-Deoxyglucose [FDG] uptake influences the incidence of distal metastases. Material and Methods: We retrospectively evaluated 18-Fluorine -Fluoro-2-Deoxyglucose Positron emission tomography integrated with computed tomography [FDG-PET/CT] of 35 patients with Non-Small cell carcinoma [NSCLC], who had come for pre-treatment staging of the disease. Results: The mean FDG uptake of the tumour was maximum Standardized Uptake value [SUV max] of 10.73. 21 of the 35 patients had metastases. Metastases to the bone was the most frequent. The Pearson correlation between the FDG uptake and incidence of metastases was 0.013, suggesting negligent linear correlation between the two. Conclusion: Non-small cell lung carcinoma tumour have a favoured spread to the bones. FDG uptake cannot be taken as an independent parameter to predict the incidence of metastases in NSCLC
Authors and Affiliations
Gokulakrishnan PR, Arunan Murali, Bhasker Raj, Venkata Sai
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