Correlation between Conners' Parent Rating Scale and autonomic functions in ADHD before and after methylphenidate
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 6
Abstract
The present study was conceived with the objective to study the correlation between the Conners' Parent Rating score and autonomic functions in children with Attention-deficit/hyperactivity disorder (ADHD) before and after treatment with Methylphenidate. ADHD is associated with autonomic dysfunction which gets further modulated by drug therapy. There are few prospective studies to evaluate the correlation between the Conners' Parent Rating score and autonomic functions before and after 12 weeks of methylphenidate treatment in drug-naive patients with ADHD. The parasympathetic reactivity was tested with E: I ratio (Deep Breathing Test) and 30:15 ratio (Heart response to standing). On the Sympathetic reactivity tests, the Increase in Systolic blood pressure (SBP) & diastolic blood pressure (DBP) on exposure to cold (Cold Pressor test) and sustained handgrip (Handgrip test) was performed on the subjects. Cold Pressor Test SBP differences showed a negative correlation with Connors Parent Rating score signifying that the children with lower ADHD scores had higher responsiveness to CPT-induced SBP changes. Posttherapy Cold Pressor Test SBP differences showed a negative correlation with Connors ARS signifying that the children with lower ADHD scores had higher responsiveness to CPT-induced SBP changes. Hence with the improvement as shown by reduction in ADHD scores, the sympathovagal balance shifts towards the sympathetic arm
Authors and Affiliations
Pramesh Dogra
Keywords
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