Correlation between diabetes autoantibodies and environmental parameters in type 1 diabetics and their siblings in Abidjan District, Ivory Coast
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 1
Abstract
Objective: The aim of this work is to determine the correlation between the presence of diabetes autoantibodies and certain environmental parameters and diet in type 1 diabetes (T1D) and their siblings. Methods: The study population consisted of 49 people, including 19 with T1D and 30 siblings of frst degree whose blood and faeces were collected. T1D were recruited from two University hospital centres in Cote d’Ivoire. Serum obtained allowed the determination of anti-ICA autoantibodies by the immunofluorescence method, anti-GAD and anti-IA2 detected by ELISA. Blood parasites were sought by the drop of thick and blood smears. Intestinal parasites were searched by the direct method, Kato and Ritchie techniques. Yeasts isolation was done on Sabouraud chloranphénicol and identifying by the chromatic Candida medium. Pinworms were sought by the anal scotch test technique. Vaccines and food were mentioned on a survey sheet. Results: The 3 diabetes autoantibodies were present in T1D and 2 combinations anti-GAD-IA2 among siblings (p<0.0001). Hand pinworms, DT1 and their siblings infected with blood parasites are respectively, intestinal parasites, yeast. The diet of T1D signifcantly different from that of siblings (p=0.031<0.05). Conclusion: There is no correlation between the presence of diabetes autoantibodies and blood and intestinal parasites, yeasts, pinworms among siblings of diabetics. Their diet should be balanced to avoid the installation of diabetes.
Authors and Affiliations
Trébissou AFJ| Pole of Biology Immunity, Pasteur Institute of Côte d’Ivoire, Abidjan, Côte d’Ivoire, Laboratory of Biochemistry-Pharmacodynamics, Faculty of Biosciences, Université Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire, Yapo-Crezoit CCA| Pole of Biology Immunity, Pasteur Institute of Côte d’Ivoire, Abidjan, Côte d’Ivoire, Yapo FA| Laboratory of Biochemistry-Pharmacodynamics, Faculty of Biosciences, Université Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire, Corresponding e-mail: fyapo@yahoo.fr, Sanogo M| Division of Diabetes and Endocrinology, Centre Hospitalier Universitaire de Yopougon, Côte d’Ivoire, Sibailly P| Diabetes Clinic, Centre Hospitalier Universitaire de Treichville, Côte d’Ivoire, Ankotché A| Diabetes Clinic, Centre Hospitalier Universitaire de Treichville, Côte d’Ivoire, Touré AO| Department of parasitology of Pasteur Institute of Côte d’Ivoire, Abidjan, Côte d’Ivoire
Keywords
Related Articles
- EP ID EP12297
- DOI -
- Views 305
- Downloads 14
EFFECT OF AGE ON TEST PERFORMANCE IN COMMUNITY DWELLING ELDERLY PEOPLE: 6 MINUTES WALK TEST AND TEN STEPS TEST
The data available in literature for test performance in elderly people are less and insufficient for use as a basis of comparison. The aim of the study was to investigate age related changes in functional performance t...
GARENOXACIN IN UNCOMPLICATED URINARY TRACT INFECTION – A CASE STUDY REPORT
Urinary tract infection (UTI) is a global problem which has increased the morbidity and mortality in both men and women. Strategies which are proposed in the management of UTIs include the use of empirical antibiotics w...
Maternal age and BMI in relation to infant birth size: a study in public health centers in the north of Iran
Birth weight is one of the best indexes for determine mother’s nutritional status and pregnancy care. The main aim of this study is determine the association between mother’s BMI and birth weight based on age in rur...
Ulcerative Colitis: Psychosocial Factors Involved
Background: This study aims to extend the knowledge regarding the psychological component of Ulcerative colitis (UC). Materials and methods: Eight questionnaires were completed and were performed deep psychosocial anamn...
DRUG UTILIZATION STUDY OF GYNECOLOGY OPD: IN A TERTIARY CARE HOSPITAL
Background: The treatment of diseases by use of essential medicines, prescribed by generic names, has been emphasized by WHO and National Health Policy of India. Drugs used in gynaecology are one of the top selling dru...