Correlation between Leptin and Uric Acid in Obese Adolescents in North Bolaang Mongondow Regency
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 11
Abstract
Abstract: Leptin is a hormonal product of the ob gene that has important roles in balancing energy regulation, reducing food intake and increasing energy use. Hyperuricemia is a state in which a person uric acid blood level is higher than normal. Obesity is a pathological condition that characterized by the excessive accumulation of body fat. Hyperuricemia associated with obesity. Uric acid is significantly associated with obesity, diabetes mellitus, hypertension and ischemic heart disease. Hyperuricemia in obese people usually happens because uric acid synthesis is increasing while excretion of uric acid by kidneys is decreasing. To determine correlation between leptin and uric acid level in obese adolescents in North Bolaang mongondow regency. This research was used cross sectional method with 52 samples taken from students high schools in North Bolaang Mongondow regency that matched the inclusion and exclusion criteria from this research. The result showed that All subjects had central obesity which consisted of 32% men and 68% women. 28,8% of subjects had hyperuricemia and 15,4% had leptin levels ≥ 40 ng / dL. Correlation test results showed that there is a positive significant correlation between leptin levels and uric acid with ρ = 0.000 and R = 0.334. there was a significant correlation between leptin levels and uric acid.
Authors and Affiliations
John P Porotuo, Aaltje E Manampiring, Joice N Engka
Keywords
Related Articles
- EP ID EP479181
- DOI -
- Views 46
- Downloads 0
Comparative Study of Heart Rate Variability Parameters in Supine Posture in Both Genders
Abstract: The aim of present study was to compare the heart rate variabilityparameters in healthy adult males and females.It is known that many factors influence the heart rate variability,one of which is gender. Gender...
Maternal and Fetal Outcome in Referred Patients to Tertiary Care Center
The objective was to study the referred obstetric cases for appropriateness and timeliness of referral and to study the maternal and perinatal outcome. Design was Prospective Observational study. The study population in...
Males vs Females – Risk of Developing Early Hypertension?
Females are at less risk of coronary heart disease, and of serious arrhythmias as compared to their male counterparts, women lagging behind men in the incidence of sudden death by 20 years. In present study, 20 healthy m...
Pattern of Soft Tissue Tumours in GMC Jammu- A one year Histopathological Study
Abstract: Soft tissue tumours constitute a large and heterogenous group of neoplasms. They are the mesenchymal proliferation that occurs in extraskeltalnonepithelial tissue of the body, excluding the viscera, covering of...
Epidemic of Dermatophytosis in India, are Topical Steroids Adding Fuel to the Fire? - Hospital Based Longitudinal Prospective Study
Abstract: Dermatophytic skin infections constitute major bulk of dermatological diseases in India. Use of topical corticosteroid is said to be compounding many aspects of clinical presentations and epidemiology of diseas...