Correlation between Liver Enzymes and Chronic Kidney Disease Iraqi Patients With or Without Hemodialysis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
In CKD patients liver enzymes to be in the lower levels of normal reference range value, while ALP is high due to renal osteodystrophy. As a result the diagnosis and follow up of liver disease in these patients are dilemma and challenging. Aims: The need for new reference ranges of liver enzymes in chronic kidney disease patients for accurate diagnosis and assessment of any liver disease and its progression. Settings and Design: A cross sectional study, which was conducted from January 2014 to January 2015. Methods and Material: Fifty patients in each group were enrolled in the current study according to inclusion criteria and each one was sent for: serum aminotranferases, total serum bilirubin, serum albumin, PT & INR, renal function test and serum electrolyte, virology screen, CBC and abdominal ultrasound. Statistical analysis used: One way ANOVA was used to analyze the statistical significance of the 3 groups. All analyzed were performed using SPSS version 22 software package. Results: The chronic kidney disease patients had lower serum aminotransferases when compared to normal population; and AST level was lower in hemodialysis patients only,while ALT levels were not significantly differed with both groups. Conclusions: A normal level of serum aminotransferases in chronic kidney disease patient does not exclude liver disease in those patients. We need new normal reference ranges of liver enzymes in chronic kidney disease patients for accurate diagnosis, assessment, monitoring, treatment, and follow up of any liver disease.
Authors and Affiliations
Ali Abdulmajid Dyab Allawi, Mohammed Yousif Mahmood, Farouq adnan Hammied
Keywords
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- EP ID EP243663
- DOI 10.9790/0853-1610057481
- Views 105
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