Correlation between retinal vascular density and visual field loss in primary chronic angle-closure glaucoma
Journal Title: Eye Science (Yanke Xuebao) - Year 2021, Vol 36, Issue 6
Abstract
[Objective:] To investigate the correlation between the retinal vessel density (VD) and the degree of visual field loss in chronic primary angle-closure glaucoma (CPACG). [Methods:] Eighty-nine CPACG patients (112 eyes) with different degrees of visual field loss were measured with optical coherence tomography angiography (OCTA) for macular VD and para-optic microcirculation VD, and the correlation between them and the degree of visual field defect were analyzed. [Results:] There was a negative correlation between the VD of the microcirculation in each zone next to the optic disc and the degree of visual field loss (r>–0.728, P<0.05). The receiver operating characteristic (ROC) and area under the curve (AUC) of the total VD of the superficial macula is 0.874. Under the condition of controlling age, intraocular pressure and vision, for every 1% decrease in the total superficial macular VD, the average visual field defect mean deviation (MD) value increases –0.639 dB. [Conclusion:] The VD of CPACG patients is linearly negatively correlated with visual field defects. OCTA can conveniently and non-invasively observe the blood flow of the fundus in patients with glaucoma. It is found that the retinal VD is reduced before visual field defects, which can be used as a reference index for early diagnosis of CPACG.
Authors and Affiliations
Qing WANG, Hong LIN, Yihua YAO, Yihua ZHU
Keywords
Related Articles
- EP ID EP763523
- DOI 10.3978/j.issn.1000-4432.2021.06.11
- Views 34
- Downloads 0
Research progress of warm compresses in the treatment of meibomian gland dysfunction
Meibomian gland dysfunction (MGD) is a common ophthalmic disease, which is the main cause of evaporative dry eye. Population-based studies have suggested that the prevalence of MGD is high in Asia, with a reported incide...
The application of assistive technology for visual impairment in low vision rehabilitation
Patients with low vision are severely impaired in visual function due to different ocular and neurological disorders, which have a serious impact on their daily activities (such as reading and driving), quality of life a...
A new diagnosis consideration of dry eye based on tear-film-oriented
Different components of the tear film work together to maintain the wettability of the ocular surface, thus maintaining eye health. When the pathological changes of these components occur, the tear film homeostasis will...
Research progress of oculomics in neurodegenerative diseases
Neurodegenerative diseases can damage the structure and function of the brain and nervous system, leading to a gradual decline in cognitive and behavioral abilities. Therefore, early diagnosis of neurological diseases ca...
Advances in wide-field fundus imaging for pachychoroid disease
Pachychoroid disease (PCD) represents a group of disorders characterized by pathological choroidal thickening. The characteristic changes include dilated choroidal vessels in Haller's layer, thinning of the choriocapilla...