CORRELATION BETWEEN SERUM GAMMA GLUTAMYL TRANSFERASE AND GESTATIONAL DIABETES MELLITUS IN PREGNANCY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 9
Abstract
BACKGROUND The incidence of Gestational Diabetes Mellitus is increasing in recent years. Gestational Diabetes Mellitus has significant maternal and perinatal mortality. Hence it is important to identify a screening test in the early pregnancy period so that preventive measures can be used to avoid maternal and fetal adverse effects. The aim of this study is to evaluate the relationship between Serum Gamma Glutamyl Transferase (Serum GGT) and Gestational Diabetes Mellitus in the first trimester. Previously many studies have been conducted showing positive correlation between them in the mid trimester of pregnancy. Here sufficient time is not available to take preventive measures. Our study aims to show the correlation between them in the first trimester itself, so that sufficient time is available to the doctor and the patient to take preventive measures to avoid perinatal and maternal morbidity. MATERIALS AND METHODS A prospective study was done in a tertiary care hospital during a period of 6 months. One hundred random pregnant women who came for booking visit were selected and Serum GGT was done. Later they were followed up with OGGT and diagnosed with GDM as per WHO criteria. RESULTS In our study, we found pregnant women in the age group of 30-40 years had higher incidence of GDM. The incidence rate of GDM in our study was 12%, which was high. Also, women with high BMI (Class 2 and Class 3) had higher incidence of GDM. A cut off of 30 U/L of Sr GGT was taken in our study. In our study of the 12 GDM patients, 10 had high Sr GGT. (83.3%) and 2 of them had normal values. Among non GDM women 2 had high Sr GGT values. A positive correlation with high GGT and GDM was done. GGT was found to be an independent risk factor for GDM especially with high FBS values. CONCLUSION GGT can be used as screening test for GDM.
Authors and Affiliations
Jyothi Prabhakar Rao, Rajini Jayakanthan V
Keywords
Related Articles
- EP ID EP611554
- DOI 10.18410/jebmh/2019/135
- Views 70
- Downloads 0
A STUDY OF AETIOLOGY, CLINICAL FEATURES, ECG, ECHOCARDIOGRAPHIC FEATURES OF CARDIAC TAMPONADE
BACKGROUND Cardiac tamponade is a life-threatening, slow or rapid compression of the heart due to the pericardial accumulation of fluid, pus, blood, because of effusion, trauma or rupture of the heart. It was an observat...
A CASE OF PIAL ARTERIO-VENOUS MALFORMATION
PRESENTATION OF CASE A 68-year-old female housewife presented with complaints ofa. Seizures since 30 years on and off b. Headache since 30 years left sided parieto-temporal Patient has been on treatment since 30 years wh...
CROSSECTIONAL STUDY OF PREVALENCE OF DYSMENORRHEA AND PRE MENSTRUAL SYNDROME IN COLLEGE STUDENTS
Dysmenorrhea or pain during menstruation is the most common gynaecological complaint among adolescents and college students. A good majority of patients with dysmenorrhea also experience pre-menstrual symptoms (PMS). The...
HIGH VAGINAL SWAB STUDY IN PRETERM LABOUR AND PRETERM PREMATURE RUPTURE OF MEMBRANES AND ITS RELATIONSHIP WITH NEONATAL SEPSIS
BACKGROUND Preterm labour is one of the most challenging obstetric complications encountered by obstetricians. Preterm delivery affects one in ten births (11%) and even greater in developing countries. In the United Stat...
COMPARISON STUDY BETWEEN ONLAY AND UNDERLAY MESHPLASTY FOR INCISIONAL HERNIA
BACKGROUND Hernia is among the oldest known afflictions of humankind, and surgical repair of the inguinal hernia is the most common general surgery procedure performed today.1 Incisional hernia is one of the most common...