CORRELATION BETWEEN THE EARLY MID-TRIMESTER (13-20 WEEKS) MATERNAL SERUM BETA-HCG LEVELS AND THE DEVELOPMENTOF GESTATIONAL HYPERTENSION LATER IN THE PREGNANCY, A PROSPECTIVE OBSERVATIONAL STUDY.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 10
Abstract
Background: Gestational hypertension is a common but potentially life threatening complication of pregnancy. Till date no accurate diagnostic modalities are available for its early prediction so that adequate timely measures could be taken for prevention, early detection and adequate management. Objective: To evaluate the role of mid-trimester maternal serum βhCG levels for the prediction of development of pre-eclampsia and its severity later in the pregnancy. Methods: The study was a prospective observational study involving a total of 178 randomly selected women, between 13 to 20 weeks of gestation. Early mid-trimester βhCG levels were estimated and absolute values converted to population based multiples of median (MOM) and development and severity of hypertension/pre-eclampsia was observed in the follow up. Results: Out of a total of 178 only 165 women could be followed till end. Among 142 women with mid-trimester βhCG levels< 2 MOM only 2 developed hypertension. Twenty three women had βhCG values >2 MOM and in this group 47.8% women developed severe hypertension (p<0.001). A positive correlation between the severity of hypertension and absolute βhCG levels more than 80000mIU/mL (88935+7835.44; t=6.058; p<0.001) was observed. The chances of caesarean delivery increased with the severity of hypertension. Whereas only 20.6% normotensive women were delivered by LSCS; 11 (55.0%) out of a total of 20 women with gestational hypertension underwent LSCS (p <0.001). Conclusion: Elevated mid-trimester maternal serum βhCG levels could be used as a predictor of development and severity of hypertension in pregnancy.
Authors and Affiliations
Basharat Hussain Pandit, Sadia Ali Wani, Syed Nawaz Ahmad, Asia Ashraf, Manjeet Arora, Shelly Batra.
Keywords
Related Articles
- EP ID EP409909
- DOI 10.21474/IJAR01/7870
- Views 59
- Downloads 0
PRODUCTION HALIEUTIQUE AU SENEGAL : CONTRIBUTION DE LA TRANSFORMATION A LE CONOMIE MARITIME ET NOUVELLES STRATEGIES POUR AMALIORER LA FERMENTATION TRADITIONNELLE DU POISSON.
La p?che et la transformation du poisson occupent une place importante dans l??conomie et l?alimentation au S?n?gal. La production halieutique nationale totale a atteint 509 215,7 tonnes en 2016 (DPM, 2016). L?essentiel...
DETECTION OF HUMAN CYTOMEGALO VIRUS AMONG MALE WITH INFERTILITY DISORDERS IN KHARTOUM STATE, SUDAN.
Background: Human pathogens have been recognized as having a considerable possible effect on male infertility. Recent studies have shown the role of viral infections as an idiopathic pathogenesis of male infertility incl...
THE DEVELOPMENT AND VALIDATION OF AN EGM2008 GEOID MODEL FOR SENEGAL.
In Senegal, the use of GPS Global Navigation Satellite Systems (GNSS) technology to give a planimetric position on the WGS84 ellipsoid has increased considerably in recent decades. However, the problem of altitude posed...
CONTROLLING BLOOD PRESSURE IN SEVER HYPERTENSION DURING LABOUR: A COMPARATIVE STUDY.
Background:Pregnancy induced hypertension with proteinuria occur in 5% of primigravidas, it remains the commonest cause of maternal mortality and substantial cause of neonatal morbidity and mortality. Pre-eclampsia is co...
INVISALIGN ? A BRIEF OVERVIEW.
As the frequency of adults seeking orthodontic treatment is increasing in the new era,more is the concern on esthetics. The traditional conventional fixed appliance although provides sufficient tooth movement it lacks es...