CORRELATION BETWEEN THE PARAMETERS OF DIFFUSION CAPACITY OF LUNG WITH DIABETIC NEPHROPATHY, A HOSPITAL BASED STUDY IN EASTERN INDIA
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 6
Abstract
Background: Diabetes mellitus is a systemic disease with complications involving eyes, kidneys, nerves and vascular system. The presence of an extensive microvasculature and abundant connective tissue raises the possibility that lung may also be a target organ in diabetes. Aims and Objectives: To compare and correlate diabetic nephropathy with parameters of diffusion capacity of lung. Methods: A total of 60 T2DM patients with or without complications of age group 35-55years and 60 age and sex matched control were included after inclusion and exclusion criteria. All subjects were evaluated for PFT with Diffusion capacity (DLCO) by single breath technique- INSPIRE HD –PFT) and status of nephropathy by microalbuminuria. DLCO was correlated with diabetic nephropathy. p<0.05 was considered as signicant. Results: There was signicant (P<0.05) changes in diffusion capacity (DLCO% and DL/VA%) in cases compared to controls and signicant deterioration of diffusion of lung in Diabetic nephropathy(microalbuminuria) and that was negatively correlated with DLCO% (r=-o.53) and DL/VA% (r=-0.66) . Conclusion: There was signicant impairment of diffusing capacity of lung in diabetic nephropathy cases compared to controls and also negative correlation found between microalbuminuria with diffusion capacity.
Authors and Affiliations
Dr. Md. Sadique Mallick, Dr. Md. Salim Uz Zaman
Keywords
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