Correlation Between The Use of Depot Medroxyprogesterone Acetate (DMPA) For 12 Months and Coagulation Factors
Journal Title: IOSR Journal of Nursing and health Science - Year 2019, Vol 7, Issue 1
Abstract
Background: Of safe motherhood initiative program, Keluarga Berencana (KB) is expected to reduce fertility rate in Indonesia. Injectable hormonal contraceptive, known as DMPA is believed to have failure rate of <0.5%. One of DMPA side effects is irregular bleeding in term of coagulation factors disruption. Objective: To assess the effects of DMPA for 12 months on coagulation factors. Methods: The design of study was cross sectional, conducted at primary health care Medan Johor, on July 2017. Forty women using DMPA for 12-16 months were selected by consecutive sampling. Data were analyzed using T-paired test. Results: Characteristics of the study mostly often encountered were 30-39 years of age group (72.5%), multiparous (82.5%), overweight (37.5%) and abnormal menstruation cycle (72.5%). The mean values of PT, TT and APTT were 13.19±0.64 s, 17.17±1.28 s, and 0.65±4.19 s respectively. Eventually, no significant correlation between the use of DMPA for 12 months and coagulation factor (p=0.948). Conclusion: There was no significant correlation between the use of DMPA for 12 months and coagulation factor (p>0,05).
Authors and Affiliations
Anisya Friska Sari Hasibuan, Delfi Lutan, Elida R Sidabutar, Letta S Lintang, Hanudse Hartono, Rhiza Z Tala
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