CORRELATION OF CARDIAC TROPONIN IN ACUTE MYOCARDIAL INFARCTION WITH LEFT VENTRICULAR DYSFUNCTION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 30
Abstract
BACKGROUND Ventricular function is the best predictor of death after an acute coronary syndrome. It serves as a marker of myocardial damage, provides information on systolic function as well as diagnosis and the prognosis. The aim of the study is to relate cardiac troponin I with left ventricular dysfunction in acute Myocardial Infarction. MATERIALS AND METHODS This was a prospective observational study on 80 patients, aged between 20-80 years who were diagnosed with acute MI. Patient details, detailed history, and clinical features along with investigation report. RESULTS Overall, the 80 participants of the study had a mean age of 60 years. 17.5% of the cases were <50 years while the majority (82.5 %) were above 50 years of age. 67.5% were males and 32.5% were females. 59 patients (73.75%) had diabetes mellitus, 44(55%) had hypertension, 33(41.25%) gave history of alcohol consumption and 29 (36.25%) gave history of smoking habits. The mean durations of diabetes mellitus and hypertension in these subjects were 6.42 years and 5.1 years respectively. 78 out of the 80 cases included in the study had HbA1c levels of >6.5% signifying poor glycaemic status. 52 of the subjects (65%) had dyslipidaemia. Advancing age along with prevalence of diabetes mellitus was found to have a strong correlation for developing an acute MI. The mean value of trop I at presentation was 19.47 ng/ml, at 6 hours was 23.36 ng/ml, and at 24 hours was 38.33 ng/ml. The 24-hour mean value of Trop I was significantly higher. Nearly 58% of the patients presented with anterior wall MI and the remaining with inferior wall MI. There was no difference in mean values of Trop I at 6 hours and 24 hours between patients with IWMI or AWMI. Mean value of ejection fraction was 42.45%. There was no statistically significant difference between mean values of LVEF among anterior and inferior wall MI patients. 82.25% of patients with STEMI had LV dysfunction. In our study positive predictive value of trop I was 100. CONCLUSION Trop I estimation serves as a simple, inexpensive and easy method of identifying LV dysfunction in MI patients and aids in further assessment and management of patients requiring further intervention.
Authors and Affiliations
Sayyid Mohammed Khilar, Dayamani Dayamani, Neha Khilar
Keywords
Related Articles
- EP ID EP570033
- DOI 10.18410/jebmh/2018/461
- Views 84
- Downloads 0
MINERAL ANALYSIS OF GIANT SUBMANDIBULAR GLAND SIALOLITHS IN COMPARISON WITH PATIENT’S SERUM PARAMETERS: A CLINICAL STUDY
BACKGROUND Sialoliths often referred to as salivary calculi constitute 0.45% in regular clinical practice and mainly characterize the ducts of parotid and submandibular salivary glands. Sialolith is composed of both orga...
HAEMODYNAMIC STABILITY OF CKD PATIENTS UNDERGOING DIALYSIS AT ISOTHERMIC DIALYSATE TEMPERATURE
BACKGROUND Chronic Kidney Disease patients undergo dialysis for their ailment, due to which they experience many complications and adverse effects. One of the most important complications is haemodynamic instability (hyp...
EFFECTIVENESS OF ACTIVE TEACHING METHODS FOR THE RESIDENTS OF PHYSICAL MEDICINE AND REHABILITATION
BACKGROUND Lecture is the most common teaching aid not only for medical undergraduates, but also specialty residents. There are many disadvantages for this type of teaching. Active teaching methods include didactic lectu...
EVALUATION OF PROPTOSIS BY USING COMPUTED TOMOGRAPHY IN A TERTIARY CARE CENTER, BURLA, SAMBALPUR, ODISHA
BACKGROUND Proptosis is defined as the abnormal anterior protrusion of the globe beyond the orbital margins.1 It is an important clinical manifestation of various orbital as well as systemic disorders. Aetiology ranging...
A RARE CASE OF ALKAPTONURIA: CASE REPORT
INTRODUCTION Alkaptonuria is a rare metabolic autosomal recessive disorder due to Homogentisic acid oxidase deficiency. There is generalized deposition of oxidized HGA in tissues mainly in fibrous and cartilaginous tissu...