Correlation of Haematological Parameters with Blood Culture in Neonatal Sepsis: A Prospective Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Sepsis is the commonest cause of neonatal mortality. It is responsible for about 30-50% of the total neonatal deaths in developing countries. The aim of present study is to find the correlation of haematological parameters with microbiological one (blood culture). Methods: The prospective, cross sectional hospital based study conducted over a period of 2 years on 250 newborns. In the setting of present study blood culture is done by a conventional method & a gram smear is also made and examined at subculture stage. Data is subjected to appropriate statistical analysis. Results: There is statistically significant association between cases of sepsis and mode of delivery. There is statistically significant association between prematurity and sepsis. Common clinical manifestations of neonatal septicaemia were feeding difficulty (75.12%), reduced movement (60%), temperature abnormality (56.1%), respiratory distress (19.02%), convulsions (18.05%), sclerema (8.78%), prolonged capillary refill time (18.54%) and redness around umbilicus (7.31%). Among the 45 culture proven babies, 22 (48.89%) babies had grown Klebsiella, of which 11:11 (M:F); 12 (26.67%) babies had grown Staph. aureus, of which 9:3 (M:F); 5 (11.11%) babies had grown Coagulase Negative Staphylococcus, of which 4:1 (M:F); 3 (6.67%) babies had grown E. coli, of which 2:1 (M:F); 2 (4.44%) babies had grown Pseudomonas, of which 1:1 (M:F); 1 (2.22%) baby had grown Enterococcus, which was a male child. Among the 45 culture proven cases, 27 (60%) were gram negative and 18 (40%) were gram positive. Conclusion: Blood culture positivity and organism isolated on culture is helpful in instituting appropriate antibiotic , to which the organism is sensitive and help to develop an antibiotic policy for the neonatal intensive care unit of institution.
Authors and Affiliations
Lakshika Chauhan, Swati Chouhan, N N Agarkar, Gurmit Singh
Keywords
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- EP ID EP538010
- DOI 10.21276/ijmrp.2018.4.2.014
- Views 78
- Downloads 0
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