Correlation of hematological parameters with ECG changes in type II diabetes mellitus
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
Diabetes mellitus results in abnormal metabolism that affects many systems of the body. It is necessary to understand the hematological & electrocardiographic changes that can occur in patients with type 2 diabetes.Materials & method:-Present cross sectional study carried out in tertiary care hospital from May 2015 to May 2017. 100 diabetic subjects (study group), 100 non-diabetic subjects (control group) were selected for study randomly from various departments of tertiary care hospital. In all study, subject’s blood was tested for HbA1c; MPV & ECG changes were recorded.Results: - There was significant difference between cases and controls for mean blood sugar level & mean HbA1c (p<0.01). Mean Platelet Volume of study group is significantly more than that of control group ( p < 0.0001**).ST segment changes, T wave inversion & Q-QS pattern were more among diabetic patient as compared to controls (p<0.01).Conclusion:-Mean HbA1c of study group is significantly more than that of control group.Mean Platelet Volume of study group is significantly more than that of control group .ECG changes suggestive of myocardial ischemia or myocardial infarction in the form of ST segment changes, T wave changes and Q-QS pattern were significantly more in the study as compared to control group. HbA1c levels and MPV values were higher in subjects with abnormal ECG than in subjects with normal ECG. Increased MPV is associated with increased risk of myocardial infarction,stroke and TIA.
Authors and Affiliations
Dr. Mukund Pujari. , Dr. Padmaja R. Desai, Mr. Pandian M
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