CORRELATION OF PORTAL VEIN DIAMETER, SPLENOMEGALY AND THROMBOCYTOPAENIA WITH GASTRO-OESOPHAGEAL VARICES IN CIRRHOTIC PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 83
Abstract
BACKGROUND The word cirrhosis comes from the Greek word kirrhos, which means orange yellow.1 Cirrhosis is a chronic disease of the liver in which diffuse destruction and regeneration of hepatic parenchymal cells and diffuse increase in connective tissue has resulted in disorganisation of the lobular architecture, which leads to various complications such as portal hypertension and its sequelae including gastro-oesophageal varices and splenomegaly, thrombocytopaenia, etc. The aim of this study is to study the correlation of portal vein diameter, splenomegaly and thrombocytopaenia with gastrooesophageal varices in cirrhotic patients. MATERIALS AND METHODS This is an observational study including 100 patients of cirrhosis attending OPD/ admitted in various wards of Guru Nanak Dev Hospital and allied group of hospitals attached to Government Medical College, Amritsar. RESULTS Most of the patients in our study had grade II oesophageal varices (29%) and the most common age distribution in patients with grade II varices is 25 - 75 years. In our study, it is seen that portal vein diameter increases with development of gastro-oesophageal varices (p-value < 0.001). Spleen size increases with formation of gastro-oesophageal varices (p-value < 0.001). Platelet count decreases with the development of gastro-oesophageal varices (p-value < 0.001). CONCLUSION It is concluded from our study that there is a positive correlation between portal vein diameter and splenomegaly with gastrooesophageal varices and an inverse relationship between thrombocytopaenia and gastro-oesophageal varices.
Authors and Affiliations
Krishan Oberoi, Upasana Upasana
Keywords
Related Articles
- EP ID EP276111
- DOI 10.14260/jemds/2017/1260
- Views 48
- Downloads 0
A CLINICAL STUDY OF ACCIDENTAL FINGERNAIL INJURIES TO THE CORNEA IN ALQUWAYIAH GENERAL HOSPITAL, RIYADH REGION, KSA
BACKGROUND Corneal abrasions result from a disruption or loss of cells in the top layer of cornea called the corneal epithelium. Traumatic corneal abrasion can be serious if neglected. Accidental poking of the eye with f...
A COMPARATIVE STUDY OF RISK FACTORS OF CARDIOVASCULAR DISEASES IN YOUNG ADULTS WITH FAMILY HISTORY OF HYPERTENSION/DIABETES MELLITUS
BACKGROUND Non-communicable chronic diseases viz. diabetes mellitus, obesity, hypertension, cardiovascular diseases are assuming importance among the adult population in both developed and developing countries. Hypertens...
CLINICAL STUDY OF CLEFT LIP AND PALATE AND RARE FACIAL CLEFTS IN UPPER ASSAM AND ARUNACHAL PRADESH
BACKGROUND Facial clefts occur in varying degree of severity and variety of patterns. It is a nightmare which every parent wants to avoid. Facial clefts occur when the structures contributing to the formation of face nam...
COMPARISON OF PROPOFOL/DEXMEDETOMIDINE FOR ASLEEP AWAKE ASLEEP TECHNIQUE FOR AWAKE CRANIOTOMIES IN TERTIARY CARE HOSPITAL
BACKGROUND Awake craniotomy is an important technique used for brain tumour excision from eloquent cortex, epilepsy foci removal surgery, deep brain stimulation, less commonly for mycotic aneurysms, A-V malformation near...
AN INSTITUTIONAL STUDY TO EVALUATE THE EFFICACY AND TOXICITY OF REIRRADIATION USING CONVENTIONAL RADIOTHERAPY FOR RECURRENT MALIGNANT DISEASE
BACKGROUND Locoregional failure is the most frequent pattern of failure in various cancer patients despite intensified treatment and it leads to death in most of the patients. Traditionally, surgery as salvage therapy fo...