Correlation of Serum Adiponectin, Fasting Serum Glucose and Serum Insulin in Samples Received in a Tertiary Care Hospital in Central India
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 8
Abstract
Aim & Objective: Adipose cells release various adipocytokinins in response to insulin resistance. The purpose of this study was to investigate any significant difference in the level of total serum adiponectin and its association with fasting insulin, and fasting serum glucose levels, which are predictors of diabetes. Material and Methods: An analytical cross sectional study with 120 subjects (60 normal healthy offsprings of diabetic parents and 60 normal healthy off-springs of non-diabetic parents) between age group of 18 to 30 years. Subjects were enrolled after applying all inclusion and exclusion criteria and written informed consent were taken. All socio-demographic data of the participants were entered in a self-designed questionnaire. Serum adiponectin was done by ELISA and fasting glucose by glucose peroxidise method. Results: The mean value of Fasting Blood Sugar in offspring of non-diabetic, single diabetic parent and both diabetic parents were 85.23(SD 5.939), 86.84(SD 6.258) and 94.95(SD 6.586). The mean value of serum adiponectin found significantly lower in offspring of both diabetic parents than offspring of single diabetic parent (0.039*) and offspring of non-diabetic parents (0.000**). Conclusion: Adiponectin has been reported as a new risk factor for the development of diabetes. When both parents are diabetic their offsprings should always be kept in follow up as they have high chances of developing hyperglycemia
Authors and Affiliations
Rohit Manyal
Keywords
Related Articles
- EP ID EP518049
- DOI -
- Views 33
- Downloads 0
Clinical profile and outcome of Infants admitted with the first episode of Urinary Tract Infection
Objectives: The primary objective was to analyze the clinical profile of infants admitted with Urinary Tract Infection (UTI), to study the adequacy of appropriate investigations and follow up these infants. The proportio...
Molecular Characterisation of HIV Associated Tuberculosis Compared to Conventional Methods
Background: Early diagnosis of pulmonary tuberculosis is difficult using conventional diagnostic method. Acid-fast bacillus (AFB) culture and smear microscopy are alone inadequate to diagnose of human immunodeficiency vi...
Effect of propylthiouracil (PTU) on serumthyroxin (T4) and triiodothyronine (T3) concentration in mature tropical toad, Bufomelanostictus
Background: The variations in results regarding plasma concentrations of thyroid hormone of mature amphibia are related to species and season as well as to other physiological and environmental factors such as sex, nutri...
Coronary Artery Disease Severity Assessment Using Urinary Dipstick Albumin Test
Coronary artery disease refers to the gradual or sudden, reversible or irreversible obstruction to the heart’s blood supply due to the plaque build-up over several years or due to vasospasm. Albuminuria is one of the rec...
Diagnostic Utility of Cell Block Method versus Cytospin Method in Pleural and Peritoneal Fluid Cytology
Background: Cytological evaluation of body cavity fluid is diagnostically challenging. Improved ethanol formalin fixative is used which offer excellent cytomorphological features. Cell blocks prepared from residual tissu...