CORRELATION OF SERUM CALCIUM LEVELS WITH GLYCATED HEMOGLOBIN IN TYPE 2 DIABETES MELLITUS PATIENTS- A COMPARATIVE STUDY
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 8
Abstract
Background: The incidence of type-2 Diabetes Mellitus has increased world-wide making it a major public health problem. Electrolyte and mineral abnormalities are common in patients with type-2 Diabetes Mellitus. Therefore, this study was undertaken to look for the correlation between HbA1c (glycated hemoglobin) and serum calcium levels in patients with type-2 Diabetes Mellitus. Aim: To study the correlation of serum calcium levels with glycated hemoglobin (HbA1c) levels in type-2 Diabetic patients. Materials and Methods: A total of 130 type 2 Diabetic patients and 130 healthy non Diabetic people of age (30-55) years were included for the study. Both fasting and post prandial blood samples were collected from the two groups and were used for fasting blood sugar, HbA1c, serum calcium and post prandial blood sugar determination. Unpaired student's t-test was used to compare the results between the diabetic and nondiabetic group. Results: The results showed a significant decrease in the serum calcium levels (p < 0.001) in the type 2 Diabetic patients when compared to the non Diabetic control group, whereas HbA1c levels were significantly increased in the diabetic group when compared to the non-diabetic group (p < 0.001). Also, type 2 Diabetic patients showed a statistically significant negative correlation (r = -0.732, P-value= 0.00) between their HbA1c and serum calcium levels. Conclusion: Type 2 Diabetic patients with poor glycemic control are at increased risk of developing hypocalcemia when compared to those with good glycemic control
Authors and Affiliations
Dr. Romy. W. Marshnil, Dr. C. Mythili
Keywords
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