CORRELATION OF SERUM CHLORIDE LEVELS WITH 30 DAY MORTALITY IN HEART FAILURE PATIENTS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 27
Abstract
BACKGROUND Heart failure is commonly associated with electrolyte imbalances. Hyponatraemia has established prognostic role in heart failure, but association of hypochloraemia is still lacking. We wanted to study the impact of admission serum chloride levels in relation to serum sodium levels in 30-day outcomes after hospitalization for acute decompensated heart failure (ADHF). METHODS Total of 405 consecutive patients with diagnosis of ADHF were assessed for serum sodium and serum chloride levels on admission within the period of 2.5 years, and divided into 3 tertiles based on serum chloride levels and observed for 30 day outcome. Continuous variables were compared using independent t-test while 𝜒2 test was used for categorical variables. pvalue ≤ 0.05 considered significant. RESULTS Mean age was found to be 62.5 yrs. Overall mortality at 30 days was 24.4% (99) and all deaths occurred in tertile 1 (serum Cl <99), suggesting strong role of hypochloraemia in mortality. Patients in tertiles 2 (99-103) and tertiles 3 (>103) exhibited 100% survival. CONCLUSIONS Mortality at 30 days in patients with ADHF is 24.4 percent and serum chloride is strongly and independently associated with poor survival in these patients and has a major contribution in the risk caused due to hyponatraemia.
Authors and Affiliations
Kader Muneer, Himanshu Gupta, Ayushi Gupta
Keywords
Related Articles
- EP ID EP668587
- DOI 10.18410/jebmh/2019/377
- Views 122
- Downloads 0
A PROSPECTIVE STUDY OF CLINICAL OUTCOME AFTER USING LIGAMENTOTAXIS IN MANAGEMENT OF DISTAL RADIUS FRACTURES
BACKGROUND A study was done to evaluate the effect of the ligamentotaxis in the management of intraarticular fractures of the distal radius. MATERIALS AND METHODS 34 patients were studied prospectively between March 2014...
EVALUATION OF PLEURAL EFFUSION
Normal pleural space between visceral and parietal pleura is lined by thin film of fluid, but excess fluid accumulation in pleural space under certain pathological condition is termed pleural effusion.1 Pleural effusions...
CT ENTEROCLYSIS VERSUS CT ENTEROGRAPHY IN THE EVALUATION OF SUSPECTED SMALL BOWEL PATHOLOGIES - A CASE SERIES
BACKGROUND With the advent of computed tomography (CT), CT enterography has become the investigation of choice for evaluating small bowel disorders, as it allows better visualization of the bowel wall. As a result, CT en...
A HISTOPATHOLOGICAL STUDY OF PROSTATE LESIONS IN JAMSHEDPUR, JHARKHAND, INDIA
BACKGROUND Cancer of the prostate is typically a disease of men older than age 50 years. It is the most common cancer in west and the 2nd leading cause of cancer death among men. The objective of this study is to evaluat...
RHABDOMYOSARCOMA OF MAXILLARY SINUS IN AN ADULT FEMALE
Rhabdomyosarcoma of Maxillary sinus is a rare tumor usually occurring in children. A 30 year old adult female patient attending the ENT department of our Hospital presented with rapidly progressing tumor arising from Lef...