Correlation of serum lipids with the severity of diabetic retinopathy

Journal Title: IP International Journal of Ocular Oncology and Oculoplasty - Year 2017, Vol 3, Issue 4

Abstract

Purpose: To measure a correlation between serum lipids and the severity of diabetic retinopathy in patients reporting to a tertiary care diabetic and endocrinology center, in western Uttar Pradesh. Method: A hospital-based, cross-sectional study conducted on 240 eyes of 120 diabetic patients presenting at our Institute of Ophthalmology. The ETDRS system was used to grade the severity of retinopathy and the serum lipid profile of each patient was procured. The data analysis was done with the help of SPSS version 16.0 using unpaired t-test, binary logistic regression analysis, one way analysis of variance (ANOVA) with Bonferroni post hoc tests. Result: A significantly increased level of total cholesterol (p=0.02), TG (p=0.0001) and LDL (p=0.0001) was found among patients with DR than without DR. The total cholesterol was found to be significantly (p<0.05) lower among the patients with mild NPDR than mild-moderate PDR, and high risk PDR. The TG level was significantly (p<0.05) different among various stages of retinopathy. The HDL was significantly (p<0.05) higher among the patients with mild NPDR than mild-moderate PDR. Similarly, the LDL level was significantly (p<0.05) lower among the patients with mild NPDR than mild-moderate PDR. Conclusion: An increased level of total cholesterol, TG and LDL was found among patients with DR than without DR. The levels of total cholesterol, TG and LDL were found to be significantly lower among the patients with mild NPDR than PDR. The HDL level was higher among the patients with mild NPDR than mild-moderate PDR.

Authors and Affiliations

Nada Nadeem Ansari, Abdul Waris, Adeeb Alam Khan, Sheelu Shafiq Siddiqi

Keywords

Related Articles

No glue no sutures - Natural hemostasis for conjunctival autografting following pterygium excision

Introduction and purpose of the study: To study the effectivity of natural hemostatic mechanism for attachment of the graft, reducing the cost as well as risks associated with the use of fibrin glue and post-op discomfor...

Correlation of serum lipids with the severity of diabetic retinopathy

Purpose: To measure a correlation between serum lipids and the severity of diabetic retinopathy in patients reporting to a tertiary care diabetic and endocrinology center, in western Uttar Pradesh. Method: A hospital-bas...

Hindrances in management of diabetic retinopathy

Aim: The aim of this study is to analyse the treatment modalities for diabetic retinopathy and their efficacy in a rural setting. Materials and Methods: Patient selection: 50 patients who presented with diabetic retinopa...

Ocular manifestations in cases of Bell’s Palsy

Introduction: Bell's Palsy accounts for around three-quarters of all cases of unilateral acute facial weakness which is diagnosed after excluding other causes of isolated facial weakness. They often cause ocular morbidit...

Download PDF file
  • EP ID EP293534
  • DOI 10.18231/2455-8478.2017.0080
  • Views 72
  • Downloads 0

How To Cite

Nada Nadeem Ansari, Abdul Waris, Adeeb Alam Khan, Sheelu Shafiq Siddiqi (2017). Correlation of serum lipids with the severity of diabetic retinopathy. IP International Journal of Ocular Oncology and Oculoplasty, 3(4), 299-303. https://europub.co.uk/articles/-A-293534