CORRELATION OF SERUM ZINC LEVELS WITH SEVERITY OF ACNE VULGARIS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 5
Abstract
BACKGROUND Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous duct characterised by polymorphic lesions of comedones, papules, pustules, nodules and cysts. It occurs most commonly in adolescents and young adults. Zinc has been used extensively both topically and systemically for the management of acne vulgaris. Zinc levels in serum and skin has received the attention of many researchers in the field. MATERIALS AND METHODS A prospective observational study was conducted in patients presenting with Acne vulgaris to the dermatology outpatient clinic of KLE Hospital in Belgaum, Karnataka between June 2011 and June 2012. A total of 70 patients whoever has given consent and satisfying inclusion criteria were included in the study. Only patients who had not taken any zinc therapy were selected for the study. Fasting venous blood was collected from each patient. The serum zinc levels of all the samples were estimated by using immunoturbidometry method. Patients were divided into two groups: Group 1: Acne vulgaris grade 1 and 2 (mild-to-moderate acne). Group 2: Acne vulgaris grade 3 and 4 (severe acne). The mean serum level of zinc in relation to severity of the disease was calculated using t-test analysis. RESULTS There was no correlation between serum zinc level and severity of acne and the results were statistically not significant (𝑃 value > 0.05). CONCLUSION There is no correlation between serum zinc levels and severity of Acne vulgaris.
Authors and Affiliations
Gunda Praneeth Kumar, Tina Priscilla
Keywords
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- EP ID EP285936
- DOI 10.14260/jemds/2018/127
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