Correlation of some Drugs of Abuse in Human Urine by EMIT and GC/MS Analysis
Journal Title: Universal Journal of Environmental Research and Technology - Year 2011, Vol 1, Issue 4
Abstract
Drug toxicology tests are most commonly performed on urine, since most drugs and their breakdown products are excreted in the urine at higher concentration. A total number of 449 inhabitant urine samples were collected from patients admitted to emergency hospital, Mansoura University (Nov 1999 to June 2005). These samples were analyzed by EMIT and GC / MS for benzodiazepine, barbiturate, opiate and cannabinoid. The aim of this work is to evaluate the usefulness of using urine immunoassay kits for detection of some drugs of abuse, and study the correlation between the results obtained by EMIT and GC / MS techniques. Results revealed that urine immunoassay kit is useful for rapid preliminary screening of abuse drug. GC / MS results confirm that 245 samples (54.56 %) are positive of the total number of samples. These positive samples by GC / MS were as follows; benzodiazepines; 159 (clonazepam, oxazepam, temazepam), barbiturates; 58 (thiobarbiturate, butabarbital, seconal) and opiates; 28 (methadone metabolite)). We conclude that GC / MS analysis must be done for accurate identification and confirmation of EMIT results. Also, GC / MS is recommended as the most suitable technique for obtaining optimum analytical results.
Authors and Affiliations
Raafat A. Mandour
Keywords
Related Articles
- EP ID EP31666
- DOI -
- Views 395
- Downloads 1
Potassium Releasing Capacity in Some Soils of Anantnag District of Kashmir
The potassium releasing capacity of fifteen soil samples of Anantnag district of Kashmir were assessed by using five chemical extractants. The decreasing order of potassium release by the different chemical extractants...
Study of Physicochemical Parameters to Determine the Limnology of Lake, Located in Thane
Study was done to determine the levels of chlorophyll-a and dissolved oxygen in lake Varhala of Thane district. The parameters that determine the levels of chlorophyll-a and DO like pH, temperature, and nitrate were als...
Effects of Water Soluble Polysaccharide of Phellinus Merrillii on Laboratory Rats (Albino Mice)
Phellinus merrillii is a non edible, very common mushroom found on a jack fruit tree mostly used in western part of Maharashtra. It is used by tribal people to cure sour mouth; excessive salivation etc. Variety of exper...
Study of Ash Slurry Percentage in High Concentration Slurry Disposal System
Fly ash disposal through high concentration ash disposal system (HCSD) is followed in many coal based thermal power plants in India. Efforts to reduce the dilution of the slurry will result in energy conservation as wel...
Sorbents Performance Efficiency Test
Crude oil spillage had been a major concern to the Nigerian government and particularly to the people of the Niger Delta region because of the devastating effects, not just on the ecosystem of the region, but also, on t...