CORRELATION OF TOTAL LEUCOCYTE COUNT, EOSINOPHIL, NEUTROPHIL AND LYMPHOCYTE COUNTS WITH PEAK EXPIRATORY FLOW RATE (PEFR) IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 91
Abstract
BACKGROUND Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in India. In COPD, there is an increased number of leucocytes suggesting a role for the inflammatory response in the clinical progression of the disease. The aim of the study is to correlate leucocyte counts with peak expiratory flow rate (PEFR) in COPD patients. MATERIALS AND METHODS This observational study was carried out among 30 COPD patients, volunteers referred from Pulmonology Department of Saveetha Hospital. The pulmonary function test was done by using a computerised spirometer and complete blood cell count was also made for all the subjects. PEFR recorded was correlated with blood parameters (TLC, neutrophils, eosinophils, lymphocytes). RESULTS There was strong negative significant correlation (-0.80) between PEFR and TLC (p < 0.05), between PEFR and absolute neutrophil count (p < 0.05), between PEFR and absolute eosinophil count (p < 0.05) and between PEFR and absolute lymphocyte count (p < 0.05). CONCLUSION The findings indicated that whenever the blood parameters (TLC, neutrophils, eosinophils and lymphocytes) increased, there was a decrease in the PEFR in COPD patients.
Authors and Affiliations
Sureshbalaji R. A, Krishna Kumar S, Lavanya R, Prem Kumar S, Sivapriya D. V, Ramaswamy C, Shyamala Thirumeni
Keywords
Related Articles
- EP ID EP278558
- DOI 10.14260/jemds/2017/1398
- Views 55
- Downloads 0
KNOWLEDGE, PRACTICE AND ACCEPTANCE OF CONTRACEPTIVES AMONG MTP SEEKERS
BACKGROUND Unplanned pregnancy is the reason behind majority of MTPs in a developing and overpopulated country like India. The unmet need for contraception still poses a challenge despite the best efforts of the Governme...
COMPARATIVE STUDY OF FOETAL AND MATERNAL OUTCOME IN CONTROL OF GESTATIONAL HYPERTENSION BY ASSESSING THE MEAN ARTERIAL PRESSURE (> 105 - < 125) AND CONVENTIONALLY TREATING BLOOD PRESSURE
BACKGROUND Hypertensive disorders complicate 5% - 10% of all pregnancies and contribute greatly to maternal and foetal morbidity and mortality. There is a lack of consensus on the classification/ definition of hypertensi...
A STUDY OF BREATHLESSNESS IN PREGNANT FEMALES IN A RURAL SETUP
AIM This cross-sectional study was done to know the number of pregnant females experiencing breathlessness. Breathlessness is a common but a less recognised symptom in pregnancy. This study was done to highlight...
A STUDY ON ANATOMY AND VARIATIONS OF SINOATRIAL NODAL ARTERY
BACKGROUND The sinoatrial nodal artery is anatomically significant because it is the landmark for the identification of the sinoatrial node (SA node), which is the natural pacemaker of heart. Origin of the SA nodal arter...
DIAGNOSTIC ACCURACY OF MAMMOGRAPHY AND ULTRASONOGRAPHY FOR BREAST DISEASES
BACKGROUND Detecting the breast pathologies, at its earliest possible stage is the ultimate goal in imaging the breast. Diagnosis chiefly includes radiological investigations like mammography and ultrasonography followed...