Correlation of urinary markers versus blood biomarkers in osteoporotic fractures
Journal Title: Indian Journal of Orthopaedics Surgery - Year 2018, Vol 4, Issue 1
Abstract
Introduction Little has been published on the biochemical changes that can cause or a predisposing factor for osteoporotic fracture The aim of the study is to assess whether there is any correlation of fracture to the level of serum parathyroid hormone serum vitamin D and urinary n telopeptideMaterials and Methods Prospective study done at Sri Ramachandra Institute of Medical Science Chennai between October 2015 to October 2017The Inclusion criteria were persons above 50 years of age and the patients above 50 who comes within 24 hrs following trivial fall fractures All patients who participated in the study underwent Dexa scan for diagnosis of osteoporosis urinary n telopeptide and biochemical tests like serum calcium serum phosphate Alkaline phosphatase 25hydroxy vitamin D and serum parathyroid The patients were divided into two groups Group I had patients without fracture and Group II had patients who had osteoporotic fracturesResults We had nearly twenty one pertrochantric fractures patients followed by sixteen distal radius patients The mean value of urinary n telopeptide was 557 in group I and 18639 in group II The mean value of serum PTH was 695 in group I and 729 in group IIConclusion Urinary marker correlates well with the osteoporotic fracture and will be a better diagnostic tool than the blood biomarkers of osteoporosisKeywords Osteoporosis Fracture Urinary telopeptide Serum Parathormone Serum Alkaline phosphatase
Authors and Affiliations
Ganesan Ganesan Ram, P. V. Vijayaraghavan
Keywords
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- EP ID EP476573
- DOI 10.18231/2395-1362.2018.0003
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