Corrigendum: Insights into the effects of hyperlipoproteinemia on cyclosporine a biodistribution and relationship to renal function
Journal Title: The AAPS Journal - Year 2006, Vol 8, Issue 4
Abstract
Authors and Affiliations
Hamidreza Montazeri Aliabadi, Tara J. Spencer, Parvin Mahdipoor, Afsaneh Lavasanifar, Dion R. Brocks
Keywords
Related Articles
- EP ID EP681833
- DOI 10.1208/aapsj080486c
- Views 82
- Downloads 0
Cytochrome P450s and other enzymes in drug metabolism and toxicity
The cytochrome P450 (P450) enzymes are the major catalysts involved in the metabolism of drugs. bioavailability and toxicity are 2 of the most common barriers in drug development today, and P450 and the conjugation enzym...
Recent progress in the computational prediction of aqueous solubility and absorption
The computational prediction of aqueous solubility and/or human absorption has been the goal of many researchers in recent years. Such anin silico counterpart to the biopharmaceutical classification system (BCS) would ha...
Pre-Existing Biotherapeutic-Reactive Antibodies: Survey Results Within the American Association of Pharmaceutical Scientists
The immunogenicity profile of a biotherapeutic is determined by a multitude of product and patient-related risk factors that can influence the observed incidence and clinical consequences of immunogenicity. Pre-existing...
Bioequivalence; Its History, Practice, and Future
In the United States, the FDA approves and grants marketing authorization of generic drugs by applying the regulatory requirements provided in the Code of Federal Regulations (CFR). The following table provides some of t...
Aqueous and cosolvent solubility data for drug-like organic compounds
Recently 2 QSPR-based in silico models were developed in our laboratories to predict the aqueous and non-aqueous solubility of drug-like organic compounds. For the intrinsic aqueous solubility model, a set of 321 structu...