Cortisol Levels and Mortality in Severe Sepsis at Tertiary Care Center Northern Western, Rajasthan
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 1
Abstract
Background: Increased cortisol results in increased vascular tone and cardiac output. These effects are necessary for the body to counteract inflammation in situations such as septic shock, where the inflammatory response is activated rapidly. Methods: Hospital based cross sectional study conducted on 50 cases admitted in medical intensive care unit of SPMC and associated group of hospitals, Bikaner with sepsis and septic shock were taken as per WHO criteria. Results: Mean serum cortisol level in survivors was 165.3746.20 and in non survivors it was 489.3368.79 and on applying student ‘t’ test, the difference was found statistically highly significant (p<0.001). Conclusion: Increased serum free cortisol was associated with high mortality.
Authors and Affiliations
Dr. Preety
Keywords
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