Cost Analysis of Ertapenem Therapy for Urinary Tract Infections and Assessment of Its Suitability for Outpatient Parenteral Antibiotic Therapy Programme in Turkey
Journal Title: Mediterranean Journal of Infection, Microbes and Antimicrobials - Year 2017, Vol 6, Issue 1
Abstract
Introduction: The primary aim of this study was to evaluate whether there was a difference between outpatient parenteral antibiotic therapy (OPAT) and inpatient parenteral antibiotic therapy (IPAT) costs of ertapenem for urinary tract infections (UTI’s) due to extended-spectrum beta-lactamase (ESBL)-producing Gram-negative bacilli, and to discuss suitability of ertapenem for OPAT programme of Turkey for the near future. Materials and Methods: A total of 53 patients hospitalized with the diagnosis of UTI and treated with ertapenem were retrospectively evaluated. The cost of ertapenem treatment as IPAT was actual costs retrieved from the hospital records. The estimated cost of the same antibiotic for the same patients as an OPAT programme was then calculated and the costs were compared. Results: The cost difference between IPAT and OPAT was ₺ 12.305 (€ 5783). Outpatient parenteral antibiotic therapy programme would provide an estimated 20% reduction in treatment costs. The estimated number of bed days saved, if the patients had received the treatment as OPAT, was calculated to be 583 days, which constitutes about 5% of the total number of hospitalization days. Conclusion: Applying ertapenem therapy through OPAT programme for UTIs caused by ESBL-producing Gram-negative bacilli will decrease the financial burden of health expenditures and the number of inpatient bed days in Turkey.
Authors and Affiliations
Bahar ÖRMEN, Nesrin TÜRKER, Nurbanu SEZAK, Zerrin KARA, Figen KAPTAN, Tuna DEMİRDAL, Melih Kaan SÖZMEN
Keywords
Related Articles
- EP ID EP689352
- DOI 10.4274/mjima.2017.7
- Views 146
- Downloads 0
Biofilm-Related Infection: Diagnosis, Treatment, and Prevention
Biofilms can cause infections associated with orthopedic devices, endotracheal tubes, intravenous catheters, urinary catheters, and tissue fillers as well as chronic wound infections, and chronic lung infections in cysti...
Evaluation of Risk Factors Associated with HBsAg and Anti-HCV Seropositivity: Results of a Nationwide Population-based Epidemiological Survey Study in Turkey
Introduction: In this study, it was aimed to evaluate factors associated with hepatitis B surface antigen (HBsAg) and anti-hepatitis C virus (HCV) positivity through the “Raising Public Awareness and Determining Epidemio...
Investigation of the Prevalence of Group A Beta-haemolytic Streptococcus and Efficiency of Streptococcus Rapid Antigen Test in Patients Prediagnosed with Acute Tonsillopharyngitis in a University Hospital
Introduction: Acute tonsillopharyngitis is the most important infectious cause of hospital admission in pediatric age groups. The aim of this study was to investigate the prevalence of group A beta-hemolytic streptococci...
Methicillin-resistant Staphylococcus aureus Septic Arthritis: A Case Report with the Possible Colchicine Effect to the Bacterial Persistence
No Abstract
Infection Control Bundles for the Prevention of Hospital Infections
The incidence of hospital-acquired infections increases due to the rising use of invasive procedures and increased length of hospital stay. The incidence of colonization and infection with multidrug-resistant microorgani...