Cost-effectiveness of GnRH antagonist implementation on hCG injection day
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2019, Vol 16, Issue 1
Abstract
Objective: To compare the outcomes of antagonist stimulation protocols and to compare the cost effectiveness. Materials and Methods: Between 2011 and December 2017, a total of 354 women who underwent intracytoplasmic sperm injection and controlled ovarian stimulation with antagonist protocols were enrolled in the study. The antagonist implementation on the day of human chorionic gonadotropin (hCG) was continued for 194 of women, whereas the antagonist was stopped 36 hours before in 160 women. The stimulation outcomes of patients and cost-effectiveness of the regimens were compared. Results: There was a significant difference between the groups in terms of number of cryopreserved embryos, mature/immature oocyte ratio, and embryo transfer cancellations (p<0.05). The median value for the mature/immature oocyte ratio was 1.1 (0.2-7.5) and 1 (0.5-15) (p=0.001), and the ET cancellation was 5.3% vs. 1% for group 1 and 2, respectively (p=0.037). There was no difference between the groups in terms of pregnancy rates (p=0.197). Conclusion: No difference was found in the clinical pregnancy rates between the two groups. For this reason, the cessation of antagonist implementation on the day of hCG seems more advantageous in terms of cost-effectiveness and fewer injections.
Authors and Affiliations
Ayşe Zehra Özdemir, Bülent Ayas, Davut Güven, Aysun Türkmen, Çağrı Gülümser
Keywords
Related Articles
- EP ID EP684584
- DOI 10.4274/tjod.galenos.2019.56255
- Views 172
- Downloads 0
Relation between uterine morphology and severity of primary dysmenorrhea
Objective: This study aimed to evaluate whether uterine dimensions including uterine volume, uterine shape, uterine length, cervix length, and cervix thickness measurements have a role in the severity of primary dysmenor...
Surgical risk assessment for gynecological oncologic patients
Objective: Preoperative surgical risk assessment is important in terms of postoperative morbidity and mortality. Therefore, it is necessary to evaluate the efficacy and safety of these surgeries via an ideal risk assessm...
How to perform and interpret the lung ultrasound by the obstetricians in pregnant women during the SARS-CoV-2 pandemic
Objective: Evidence for the use of lung ultrasound scan (LUS) examinations in coronavirus 2019 pneumonia is rapidly growing. The safe and non-ionizing nature of LUS drew attention, particularly for pregnant women. This s...
Local uterine resection with Bakri balloon placement in placenta accreta spectrum disorders
Objective: Placenta accreta spectrum (PAS) is a potentially life-threatening condition characterized by the abnormal adherence of the placenta to the implantation site. We sought to evaluate the efficacy, surgical feasib...
Anatomic variations of the Uterine Artery. Review of the literature and their clinical significance
Uterine arteries are the main vessels supplying blood to the uterus. Mainly, they originate from the anterior trunk of the internal iliac artery. Uterine arteries play an important role in pregnancy as well as transcathe...