Crohn’s Disease: Pathophysiology, and Management
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 11
Abstract
<strong>Background:</strong> The incidence of crohn’s disease reaches up to 20 per 100,000 people per year, with a median age of 30 years, and is higher in the developed world. Although the exact cause and pathophysiology is unknown, several environmental and genetic factors have been linked with higher risk or severity of the disease. <br /> <strong>Methodology:</strong> We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: crohn’s disease, inflammatory bowel disease, genetics of crohn’s disease, diagnosis of IBD, management crohn’s disease<em><br /> </em><strong>Aim of the study:</strong> In this review, we aim to study the pathophysiology, diagnosis and management of crohn’s disease. We will pay special attention to the newer biological drugs used in management. <br /> <strong>Conclusion:</strong> Crohn’s disease is usually managed with medical treatment, although many patients will need to undergo surgery at least once. Treatment usually aims at the induction and maintenance of a remission without the excessive use and dependence of steroids. Achieving higher quality of life is the main goal of any modality of treatment.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583766
- DOI 10.12816/ejhm.2018.9407
- Views 83
- Downloads 0
Knowledge, Attitude and Practices About Pneumococcal Infection among Algerian Hajj Pilgrims
<strong>Background: </strong>Hajj attendance increases the risk of respiratory infections including pneumonia. Pneumococcal infections are caused by Streptococcus pneumonia, a gram-positive, catalase-negative organism no...
Comparative Study between Augmentation Skin Mastopexy versus Augmentation Glandular mastopexy after Massive Weight Loss
Background: an increase in the number of massive weight loss patients resulted in increase of body contouring surgery including breast reshaping. Aim of the study: it was to compare two procedures of augmentation skin ma...
Assessing Awareness about Diabetes Mellitus among Attendees of Primary Health Care Centers, Makkah, Saudi Arabia
Background: diabetes is well studied in Saudi Arabia; however, there seems to be little research in the area of awareness, education and health care delivery. Objectives: to assess the awareness about diabetes mellitus...
Knowledge, Attitude and Practice of Pharmacists
<strong>Background:</strong> Dietary supplement "DS" products are sold in the pharmacies very widely. However, there is no specific approval or definition to the legal and scientific usage of such products. <strong> </s...
Multiple Myeloma: A retrospective Analysis of the Patients Treated at Ain Shams University Clinical Oncology Department with a Review of the Literature
<strong>Background: </strong>multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow leading to bone destruction and marrow failure. Multiple myeloma accounts for about 1.8% of all ca...