Crush Smear Cytology: A Rapid Diagnostic Technique in the Intraoperative Diagnosis of CNS Tumours
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Cytology has been shown to be of great value in intraoperative consultations of central nervous system (CNS) pathology. Intraoperative smear cytology provides a rapid and reliable intraoperative diagnosis and guidance to the neurosurgeon during surgical resection and lesion targeting. It also helps the surgeon to monitor and modify the approach at surgery. The current study was undertaken to assess the utility of intraoperative crush smear cytology and to correlate with the final histopathological diagnosis along with brief description of the cytomorphological features of commonly found brain tumours in smear preparation. It included 110 cases of CNS neoplasm which were subjected to intraoperative smear cytology. Smears were prepared from the biopsy samples sent in wet cotton pad and stained by the Haematoxylin and Eosin stain. The cytomorphological features were noted and correlated with final histopathological diagnosis. Complete correlation between intraoperative cytological and histopathological diagnosis was achieved in 89.6% of the cases. A reduction of diagnostic accuracy was seen in oligodendrogliomas and mixed gliomas (22.2%). Smear technique is a fairly accurate, relatively safe, rapid, simple, easily reproducible, and cost effective tool to diagnose brain tumours.
Authors and Affiliations
Dr Sarat Das
Keywords
Related Articles
- EP ID EP212194
- DOI -
- Views 76
- Downloads 0
Corticosteroids-Induced Bradycardia: A Case Report & Literature Review
Sinus corticosteroids-induced bradycardia with high dose steroids has been reported in literature. Although the association is still not clearly understood but several mechanisms have been prompted to explain causality....
Study on Aetiological Profile of Neonatal Sepsis in a Tertiary Care Hospital in Eastern India an Original Article
Introduction-Neonatal sepsis is a major cause of neonatal mortality and morbidity. For proper management knowledge of the pattern of etiological agents and their sensitivity pattern is crucial. The aim of this study was...
Effects of Addition of Clonidine to Bupivacaine in Spinal Anaesthesia for Abdominal Hysterectomy
Hyperbaric bupivacaine is a commonly used local anaesthetic for subarachnoid blocks. Several additives are added to prolong the action of intrathecal bupivacaine. We evaluated the effects of addition of 60μgms clonidine...
Contraceptive Awareness in Antenatal Women Attending Outpatient Department in a Tertiary Care Hospital
Introduction: Contraception is a major component of reproductive health and reproductive health services that empower women will reduce the social and economic disruption in the society. The aim of the study was to asses...
Knowledge, Attitude, and Practice of General Population Towards CVD in Saudi Arabia
According to American Board of Preventive Medicine: “Preventive Medicine is the specialty of medical practice that focuses on the health of individuals, communities, and defined populations. Its goal is to protect, promo...